Evaluation of Clinical Outcomes After Revascularization in Patients With Chronic Limb-Threatening Ischemia: Results From a Prospective National Cohort Study (RIVALUTANDO).
Aged
Amputation, Surgical
Cardiovascular Agents
/ therapeutic use
Chronic Disease
Endovascular Procedures
/ adverse effects
Female
Humans
Ischemia
/ diagnostic imaging
Italy
Limb Salvage
Male
Peripheral Arterial Disease
/ diagnostic imaging
Prospective Studies
Recurrence
Registries
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome
Vascular Surgical Procedures
/ adverse effects
chronic limb-threatening ischemia
limb salvage
medical treatment
peripheral arterial disease
revascularization
Journal
Angiology
ISSN: 1940-1574
Titre abrégé: Angiology
Pays: United States
ID NLM: 0203706
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
pubmed:
8
1
2021
medline:
11
5
2021
entrez:
7
1
2021
Statut:
ppublish
Résumé
We evaluated the outcomes of revascularization in patients with chronic limb-threatening ischemia (CLTI) treated in real-world settings. This is a prospective multicenter cohort study with 12-month follow-up enrolling patients (n = 287) with CLTI undergoing open, endovascular, or hybrid lower extremity revascularization. The primary end point was amputation-free survival (AFS) at 12 months. Cox proportional analysis was used to determine independent predictors of amputation and restenosis. At 30 days, major adverse cardiovascular and major adverse limb events (MALE) rates were 3.1% and 2.1%, respectively. At 1 year, the overall survival rate was 88.8%, the AFS was 86.6%, and the primary patency was 70.5%. Freedom from MALE was 62.5%. After multivariate analysis, smoking (hazard ratio [HR] = 2.2,
Identifiants
pubmed: 33406850
doi: 10.1177/0003319720980619
doi:
Substances chimiques
Cardiovascular Agents
0
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
480-489Investigateurs
Angiletta G
(A)
Rivellini C
(R)
Pane B
(P)
Spinella G
(S)
Pipitò N
(P)
Spinelli D
(S)
Derone G
(D)
Kahlberg A
(K)
Carta N
(C)
Lauricella A
(L)
Maresca L
(M)
Antonello M
(A)
Piazza M
(P)
Bonvini S
(B)
Wassermann V
(W)
Trani A
(T)
Barresi A
(B)
Di Citra G
(DC)
Spinelli F
(S)
Montelione N
(M)
Paroni G
(P)
Magistro G
(M)
Ceriello D
(C)
Merlo M
(M)
Giordano F
(G)
Ruzzi U
(R)
Mazzitelli G
(M)
Mele M
(M)
Giannace G
(G)
Alba G
(A)
Grottola G
(G)
Pazzaglia M
(P)
Giubbolini G
(G)
Baldi B
(B)
Guerrieri W
(G)
Benevento D
(B)
Cappelli A
(C)