Mild hyponatremia is associated with low skeletal muscle mass, physical function impairment, and depressive mood in the elderly.
Balance impairment
Depression
Electrolyte disorder
Gait instability
Grip strength
Hyponatremia
Journal
BMC geriatrics
ISSN: 1471-2318
Titre abrégé: BMC Geriatr
Pays: England
ID NLM: 100968548
Informations de publication
Date de publication:
06 01 2021
06 01 2021
Historique:
received:
01
08
2020
accepted:
10
12
2020
entrez:
7
1
2021
pubmed:
8
1
2021
medline:
24
4
2021
Statut:
epublish
Résumé
Mild hyponatremia (serum sodium 130-135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive function remains to be clarified. Therefore, here we investigated the association of mild hyponatremia with skeletal muscle mass, physical function, and cognitive function in the elderly. We enrolled 75 participants with mild hyponatremia and 2907 with normonatremia (serum sodium, 136-145 mEq/L) aged ≥70 years who visited the Memory Disorder Outpatient Center of Japan's National Center for Geriatrics and Gerontology. Skeletal muscle mass index (SMI), grip strength (GS), walking speed (WS), one-leg standing (OLS) test times, and neuropsychological test scores were determined. One-way analysis of covariance showed that elderly participants with mild hyponatremia had lower SMI (7.1 ± 0.2, 7.2 ± 0.2 kg/m Our results suggest that elderly people with even mild hyponatremia had physical function impairment and depressive mood.
Sections du résumé
BACKGROUND
Mild hyponatremia (serum sodium 130-135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive function remains to be clarified. Therefore, here we investigated the association of mild hyponatremia with skeletal muscle mass, physical function, and cognitive function in the elderly.
METHODS
We enrolled 75 participants with mild hyponatremia and 2907 with normonatremia (serum sodium, 136-145 mEq/L) aged ≥70 years who visited the Memory Disorder Outpatient Center of Japan's National Center for Geriatrics and Gerontology. Skeletal muscle mass index (SMI), grip strength (GS), walking speed (WS), one-leg standing (OLS) test times, and neuropsychological test scores were determined.
RESULTS
One-way analysis of covariance showed that elderly participants with mild hyponatremia had lower SMI (7.1 ± 0.2, 7.2 ± 0.2 kg/m
CONCLUSIONS
Our results suggest that elderly people with even mild hyponatremia had physical function impairment and depressive mood.
Identifiants
pubmed: 33407209
doi: 10.1186/s12877-020-01955-4
pii: 10.1186/s12877-020-01955-4
pmc: PMC7788730
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
15Subventions
Organisme : National Center for Geriatrics and Gerontology
ID : 30-1
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