Bronchoscopic diagnosis and treatment of endobronchial carcinoid: case report and review of the literature.

Adult Bronchi Bronchial Neoplasms / diagnostic imaging Bronchoscopy Carcinoid Tumor / surgery Humans Male Pneumonectomy

Journal

European respiratory review : an official journal of the European Respiratory Society
ISSN: 1600-0617
Titre abrégé: Eur Respir Rev
Pays: England
ID NLM: 9111391

Informations de publication

Date de publication:
31 Mar 2021
Historique:
received: 23 04 2020
accepted: 02 08 2020
entrez: 7 1 2021
pubmed: 8 1 2021
medline: 25 11 2021
Statut: epublish

Résumé

Carcinoid tumours are rare neuroendocrine neoplasms that mostly occur in younger adults with low tendencies to metastasise. Based on their histological characteristics, they are divided into typical and atypical subtypes. The most common presenting symptoms are due to central airway obstruction. The first step in the diagnostic assessment should be a computed tomography (CT) scan, as it provides information both for local tumour extent and lymph node involvement. Bronchoscopy is the main tool for histological confirmation, evaluation of bronchial wall invasion and removal of endobronchial manifestation with subsequent resolution of atelectasis. Endobronchial ultrasound may be necessary to rule out lymph node metastasis. Somatostatin receptor scintigraphy in combination with CT can rule out further metastatic disease.Surgical resection using parenchyma-sparing techniques remains the gold standard for treatment. For selected patients, endobronchial therapy could be an alternative for minimal invasiveness. Long-term follow-up is suggested due to the high likelihood of recurrence.Here, we describe our clinical experience in a 35-year-old male patient who originally presented with haemoptysis and a central polypoid tumour in the left main bronchus revealed by a CT scan. The histological characteristics were indicative of a typical carcinoid. The patient was treated using an endobronchial approach only. No complications and no recurrences have been observed in a follow-up of 2 years.

Identifiants

DOI: 10.1183/16000617.0115-2020 PMID: 33408086 PMC: PMC9488937
pubmed: 33408086
pii: 30/159/200115
doi: 10.1183/16000617.0115-2020
pmc: PMC9488937
pii:
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright ©ERS 2021.

Déclaration de conflit d'intérêts

Conflict of interest: A. Papaporfyriou reports grants from European Respiratory Society, during the conduct of the study. Conflict of interest: J. Domayer has nothing to disclose. Conflict of interest: M. Meilinger has nothing to disclose. Conflict of interest: I. Firlinger has nothing to disclose. Conflict of interest: G-C. Funk has nothing to disclose. Conflict of interest: U. Setinek has nothing to disclose. Conflict of interest: K. Kostikas has nothing to disclose. Conflict of interest: A. Valipour has nothing to disclose.

Références

Hum Pathol. 2004 Jul;35(7):825-31
pubmed: 15257545
Chest. 2006 Sep;130(3):710-8
pubmed: 16963667
J Thorac Cardiovasc Surg. 2006 Jul;132(1):113-5
pubmed: 16798310
Eur J Nucl Med Mol Imaging. 2014 May;41(5):856-64
pubmed: 24435773
Chest. 2004 Sep;126(3):959-65
pubmed: 15364779
Lung Cancer. 2011 Jan;71(1):34-41
pubmed: 20462655
Surgery. 1997 Oct;122(4):801-8
pubmed: 9347859
Thorax. 2015 May;70(5):468-72
pubmed: 25777586
J Thorac Cardiovasc Surg. 1994 Jan;107(1):1-6; discussion 6-7
pubmed: 8283871
J Bronchology Interv Pulmonol. 2020 Jul;27(3):184-189
pubmed: 31876538
Ann Thorac Surg. 2013 Oct;96(4):1156-1162
pubmed: 23915584
J Thorac Cardiovasc Surg. 1972 Sep;64(3):413-21
pubmed: 5054879
Hum Pathol. 2000 Oct;31(10):1255-65
pubmed: 11070119
Medicine (Baltimore). 2019 Mar;98(10):e14769
pubmed: 30855482
Biochim Biophys Acta. 2012 Dec;1826(2):255-71
pubmed: 22579738
Thorac Cardiovasc Surg. 2005 Jun;53(3):168-72
pubmed: 15926097
J Thorac Oncol. 2011 Sep;6(9):1613-4
pubmed: 21849858
Mt Sinai J Med. 2006 Oct;73(6):884-6
pubmed: 17117316
Chest. 1995 Feb;107(2):556-8
pubmed: 7842794
J Bronchology Interv Pulmonol. 2012 Jan;19(1):29-34
pubmed: 23207260
Ann Oncol. 2015 Aug;26(8):1604-20
pubmed: 25646366
Int J Surg. 2016 Sep;33 Suppl 1:S30-5
pubmed: 27255131
Cancer. 2001 Jun 1;91(11):2104-9
pubmed: 11391591
Ann Thorac Surg. 2004 May;77(5):1781-5
pubmed: 15111186
BMC Pulm Med. 2019 Sep 2;19(1):168
pubmed: 31477066
Chest. 2001 Jul;120(1):26-31
pubmed: 11451811
Ann Thorac Surg. 2000 Jul;70(1):258-63
pubmed: 10921719
Radiographics. 2002 Mar-Apr;22(2):351-65
pubmed: 11896225
Lung India. 2015 Sep-Oct;32(5):511-4
pubmed: 26628773
Thorac Cardiovasc Surg. 2016 Mar;64(2):166-71
pubmed: 25984778
Chest. 2006 Nov;130(5):1405-11
pubmed: 17099017
Can Respir J. 2015 Jan-Feb;22(1):16
pubmed: 25664455
Thorac Cancer. 2016 Nov;7(6):633-638
pubmed: 27755793
Chest. 2001 Jun;119(6):1647-51
pubmed: 11399686
Lung Cancer. 2019 Aug;134:85-95
pubmed: 31320001
Tumour Biol. 2014 Sep;35(9):8369-77
pubmed: 24850179
Kardiochir Torakochirurgia Pol. 2017 Dec;14(4):225-229
pubmed: 29354173
Eur J Cardiothorac Surg. 2007 Feb;31(2):192-7
pubmed: 17196822
Ann Thorac Surg. 2010 Mar;89(3):998-1005
pubmed: 20172187
Eur J Cardiothorac Surg. 2015 Jul;48(1):55-64
pubmed: 25406425
Ann Surg Oncol. 2003 Jul;10(6):697-704
pubmed: 12839856
Eur Respir J. 2016 Feb;47(2):607-14
pubmed: 26541529
Eur J Cardiothorac Surg. 2015 Sep;48(3):441-7; discussion 447
pubmed: 25564217
Hell J Nucl Med. 2014 Jan-Apr;17(1):7-9
pubmed: 24563874
J Thorac Oncol. 2015 Mar;10(3):479-85
pubmed: 25371080
Diagn Ther Endosc. 2009;2009:782961
pubmed: 20169101
Ann Thorac Surg. 2002 Sep;74(3):851-8; discussion 858-9
pubmed: 12238850
Eur J Cardiothorac Surg. 2011 Apr;39(4):549-54
pubmed: 21282063
Respiration. 2018;96(2):204
pubmed: 29953990
Cancer. 2009 Oct 1;115(19):4434-41
pubmed: 19562772
Med Glas (Zenica). 2017 Feb 1;14(1):61-66
pubmed: 27917852
Eur Respir J. 2011 Jul;38(1):231-2; author reply 232-3
pubmed: 21719504
Respiration. 2018;95(4):220-227
pubmed: 29433123
BMJ Open Respir Res. 2015 Jul 15;2(1):e000090
pubmed: 26203359
Dtsch Arztebl Int. 2015 Jul 6;112(27-28):479-85
pubmed: 26214234
J Thorac Dis. 2018 Jul;10(7):4204-4211
pubmed: 30174865
Clinics (Sao Paulo). 2017 Jul;72(7):438-448
pubmed: 28793005
J Thorac Cardiovasc Surg. 2002 Feb;123(2):303-9
pubmed: 11828290
Thorac Surg Clin. 2014 Aug;24(3):257-66
pubmed: 25065926
J Thorac Dis. 2015 Apr;7(Suppl 2):S163-71
pubmed: 25984363
Chest. 2007 Jan;131(1):255-60
pubmed: 17218584
Thorac Cardiovasc Surg. 2010 Feb;58(1):32-7
pubmed: 20072974

Auteurs

Anastasia Papaporfyriou (A)

Dept of Respiratory and Critical Care Medicine, Karl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna, Austria dranastp@gmail.com.
Respiratory Medicine Dept, University of Ioannina Medical School, Ioannina, Greece.

Julian Domayer (J)

Dept of Respiratory and Critical Care Medicine, Karl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna, Austria.

Michael Meilinger (M)

Dept of Respiratory and Critical Care Medicine, Karl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna, Austria.

Irene Firlinger (I)

Dept of Respiratory and Critical Care Medicine, Karl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna, Austria.

Georg-Christian Funk (GC)

Karl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, 4 Medizinische Abteilung, Wilhelminenspital, Vienna, Austria.

Ulrike Setinek (U)

Institute for Pathology and Microbiology, Wilhelminenspital, Vienna, Austria.

Konstantinos Kostikas (K)

Respiratory Medicine Dept, University of Ioannina Medical School, Ioannina, Greece.
ORCID: 0000-0003-0774-3942

Arschang Valipour (A)

Dept of Respiratory and Critical Care Medicine, Karl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna, Austria.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Bronchoscopic diagnosis and treatment of...
questionsmedicales.fr › Appareil respiratoire › Poumon › Bronches › Bronchoscopic diagnosis and treatment of...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Tumeurs de l'appareil respiratoire › Tumeurs du poumon › Tumeurs des bronches › Bronchoscopic diagnosis and treatment of...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie thoracique › Procédures de chirurgie pulmonaire › Bronchoscopie › Bronchoscopic diagnosis and treatment of...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroendocrines › Tumeur carcinoïde › Bronchoscopic diagnosis and treatment of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Bronchoscopic diagnosis and treatment of...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie thoracique › Procédures de chirurgie pulmonaire › Pneumonectomie › Bronchoscopic diagnosis and treatment of...