Impacts of Short-Term Antibiotic Withdrawal and Long-Term Judicious Antibiotic Use on Resistance Gene Abundance and Cecal Microbiota Composition on Commercial Broiler Chicken Farms in Québec.

antibiotic withdrawal commercial broiler chickens conventional program drug-free program health judicious antibiotic use microbiota resistance gene

Journal

Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658

Informations de publication

Date de publication:
2020
Historique:
received: 30 03 2020
accepted: 19 11 2020
entrez: 7 1 2021
pubmed: 8 1 2021
medline: 8 1 2021
Statut: epublish

Résumé

The ever-increasing problem of antibiotic resistance makes routine use of antibiotics in animal production no longer considered as a reasonable and viable practice. The Chicken Farmers of Canada have developed and are implementing an Antimicrobial Use Reduction Strategy, which has the ultimate goal of eliminating the preventive use of medically important antibiotics in broiler chicken and turkey production. However, very little is known about the real overall impact of an antibiotic use reduction strategy in complex ecosystems, such as the bird intestine or the commercial broiler chicken farm. The main objectives of the present study were to compare the abundance of antibiotic resistance-encoding genes, characterize the intestinal microbiota composition, and evaluate the presence of

Identifiants

DOI: 10.3389/fvets.2020.547181 PMID: 33409294 PMC: PMC7779680
pubmed: 33409294
doi: 10.3389/fvets.2020.547181
pmc: PMC7779680
doi:

Types de publication

Journal Article

Langues

eng

Pagination

547181

Informations de copyright

Copyright © 2020 Turcotte, Thibodeau, Quessy, Topp, Beauchamp, Fravalo, Archambault and Gaucher.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Nutrients. 2020 Jan 13;12(1):
pubmed: 31941016
J Food Prot. 2011 Oct;74(10):1639-48
pubmed: 22004810
Nat Rev Microbiol. 2010 Apr;8(4):260-71
pubmed: 20208551
BMJ Glob Health. 2019 Aug 31;4(4):e001710
pubmed: 31543995
Antimicrob Agents Chemother. 2001 Nov;45(11):3223-5
pubmed: 11600385
Vet Res. 2001 May-Aug;32(3-4):261-73
pubmed: 11432417
Front Vet Sci. 2018 Oct 23;5:254
pubmed: 30406117
Microb Biotechnol. 2011 Jul;4(4):503-12
pubmed: 21375722
Lancet Infect Dis. 2016 Feb;16(2):161-8
pubmed: 26603172
J Bacteriol. 2008 Jul;190(14):5095-100
pubmed: 18487337
Clin Infect Dis. 2001 Sep 15;33 Suppl 3:S161-9
pubmed: 11524714
Antimicrob Agents Chemother. 2000 Aug;44(8):2231-2
pubmed: 11023445
Poult Sci. 2015 Aug;94(8):1791-801
pubmed: 26047674
Appl Environ Microbiol. 2014 May;80(10):3258-65
pubmed: 24632259
ISME J. 2012 Aug;6(8):1621-4
pubmed: 22402401
Front Microbiol. 2016 Dec 19;7:2033
pubmed: 28066358
Microb Drug Resist. 2007 Summer;13(2):135-41
pubmed: 17650967
Avian Pathol. 2010 Apr;39(2):117-21
pubmed: 20390546
Vet Microbiol. 2012 Sep 14;159(1-2):155-62
pubmed: 22487456
Microorganisms. 2019 Aug 22;7(9):
pubmed: 31443457
PLoS One. 2017 Feb 21;12(2):e0171642
pubmed: 28222110
Comput Struct Biotechnol J. 2018 Mar 15;16:131-139
pubmed: 30026889
J Antimicrob Chemother. 2010 Feb;65(2):350-60
pubmed: 19900952
Appl Environ Microbiol. 2014 Nov;80(22):6898-907
pubmed: 25172864
Front Microbiol. 2017 Nov 10;8:2219
pubmed: 29209285
Antimicrob Agents Chemother. 2003 Oct;47(10):3214-21
pubmed: 14506033
Can J Microbiol. 2019 Jan;65(1):34-44
pubmed: 30248271
Front Vet Sci. 2019 Apr 17;6:114
pubmed: 31058171
PeerJ. 2016 Oct 18;4:e2584
pubmed: 27781170
PLoS One. 2012;7(9):e44449
pubmed: 22970221
Anaerobe. 2016 Jun;39:105-13
pubmed: 27012900
Euro Surveill. 2016;21(6):
pubmed: 26898350
Int J Antimicrob Agents. 2009 Aug;34(2):142-7
pubmed: 19324527
Can Vet J. 2012 Dec;53(12):1289-300
pubmed: 23729827
Can Commun Dis Rep. 2017 Nov 02;43(11):220-223
pubmed: 29770050
Sci Total Environ. 2017 Jun 1;587-588:214-222
pubmed: 28242221
Microorganisms. 2019 Sep 20;7(10):
pubmed: 31547108
Vet Microbiol. 2017 May;203:149-157
pubmed: 28619137
BMC Microbiol. 2015 Oct 19;15:219
pubmed: 26482797
Gut Pathog. 2013 Aug 13;5(1):23
pubmed: 23941657
Int J Med Microbiol. 2002 Jul;292(2):81-94
pubmed: 12195739
Appl Microbiol Biotechnol. 2017 Jun;101(11):4547-4559
pubmed: 28243710
Antimicrob Agents Chemother. 1999 Apr;43(4):925-9
pubmed: 10103201
PLoS One. 2015 Jul 10;10(7):e0131978
pubmed: 26161743
Front Microbiol. 2017 May 17;8:881
pubmed: 28567032

Auteurs

Catherine Turcotte (C)

Research Chair in Meat Safety, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Alexandre Thibodeau (A)

Research Chair in Meat Safety, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Sylvain Quessy (S)

Research Chair in Meat Safety, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Edward Topp (E)

London Research and Development Centre, Agriculture and Agri-Food Canada, London, ON, Canada.
Department of Biology, University of Western Ontario, London, ON, Canada.

Guy Beauchamp (G)

Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Philippe Fravalo (P)

Research Chair in Meat Safety, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.
Pôle Agroalimentaire du Cnam, Conservatoire National des Arts et Métiers, Paris, France.

Marie Archambault (M)

Swine and Poultry Infectious Diseases Research Centre, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Marie-Lou Gaucher (ML)

Research Chair in Meat Safety, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Classifications MeSH