Experimental peri-implantitis around titanium implants with a chemically modified surface with a monolayer of multi-phosphonate molecules: a preclinical in vivo investigation.
Animal model
Dental implants
Experimental peri-implantitis
Histology
Histometric analysis
Implant surface
Monophosphonate layer
SurfLink
Wound chamber
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
21
09
2020
accepted:
24
11
2020
pubmed:
8
1
2021
medline:
25
5
2021
entrez:
7
1
2021
Statut:
ppublish
Résumé
The purpose of this experimental in vivo investigation was to evaluate the influence of modifying the implant surface by adding a monolayer of multi-phosphonate molecules on the development of experimental peri-implantitis. Eight beagle dogs received 5 tests and 5 control implants each following a split-mouth design 3 months after premolar and molar extraction. On the most mesial implant of each side, a 3-mm buccal dehiscence was artificially created. Experimental peri-implantitis was induced by silk ligatures over a 4-month period; after ligature removal, peri-implantitis was left to progress for another 4 months without plaque control. Clinical, histological, and radiographic outcomes were evaluated. Radiographically, both implant groups showed a similar bone loss (BL) at the end of the induction and progression phases. BL measured on the histological sections of the test and control groups was 3.14 ± 0.42 mm and 3.26 ± 0.28 mm, respectively; the difference was not statistically significant (p > 0.05). The remaining buccal bone to implant contact (bBIC) percentage of the test and control groups was 59.38 ± 18.62 and 47.44 ± 20.46%, respectively; the difference, however, was not statistically significant (p > 0.05). Bone loss observed at dehiscent sites compared to non-dehiscent ones showed no statistically significant difference (p > 0.05). Addition of a monophosphonate layer to a moderately rough implant surface did not affect development of experimental peri-implantitis. Influence of implant surface on peri-implantitis may condition implant selection by the clinician, especially on patients with disease risk factors. In that sense, monophosphate layer implants do not show higher peri-implantitis risk than control implants.
Identifiants
pubmed: 33409690
doi: 10.1007/s00784-020-03708-4
pii: 10.1007/s00784-020-03708-4
doi:
Substances chimiques
Dental Implants
0
Organophosphonates
0
Titanium
D1JT611TNE
Types de publication
Journal Article
Langues
eng
Pagination
3789-3800Références
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