Incremental diagnostic value of color-coded virtual non-calcium dual-energy CT for the assessment of traumatic bone marrow edema of the scaphoid.
Bone marrow edema
Fracture
Magnetic resonance imaging
Multidetector computed tomography
Scaphoid
Journal
European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
13
07
2020
accepted:
18
11
2020
revised:
05
10
2020
pubmed:
8
1
2021
medline:
24
6
2021
entrez:
7
1
2021
Statut:
ppublish
Résumé
To investigate the diagnostic accuracy of color-coded dual-energy CT virtual non-calcium (VNCa) reconstructions for the assessment of bone marrow edema (BME) of the scaphoid in patients with acute wrist trauma. Our retrospective study included data from 141 patients (67 women, 74 men; mean age 43 years, range 19-80 years) with acute wrist trauma who had undergone third-generation dual-source dual-energy CT and 3-T MRI within 7 days. Eight weeks after assessment of conventional grayscale dual-energy CT scans for the presence of fractures, corresponding color-coded VNCa reconstructions were independently analyzed by the same six radiologists for the presence of BME. CT numbers on VNCa reconstructions were evaluated by a seventh radiologist. Consensus reading of MRI series by two additional radiologists served as the reference standard. MRI depicted 103 scaphoideal zones with BME in 76 patients. On qualitative analysis, VNCa images yielded high overall sensitivity (580/618 [94%]), specificity (1880/1920 [98%]), and accuracy (2460/2538 [97%]) for assessing BME as compared with MRI as reference standard. The interobserver agreement was excellent (κ = 0.98). CT numbers derived from VNCa images were significantly different in zones with and without edema (p < 0.001). A cutoff value of - 46 Hounsfield units provided a sensitivity of 91% and specificity of 97% for differentiating edematous scaphoid lesions. Receiver operating characteristic curve analysis revealed an overall area under the curve of 0.98. Qualitative and quantitative analyses showed excellent diagnostic accuracy of color-coded VNCa reconstructions for assessing traumatic BME of the scaphoid compared to MRI. • Color-coded virtual non-calcium (VNCa) reconstructions yield excellent diagnostic accuracy in assessing bone marrow edema of the scaphoid. • VNCa imaging enables detection of non-displaced fractures that are occult on standard grayscale CT. • Diagnostic confidence is comparable between VNCa imaging and MRI.
Identifiants
pubmed: 33409799
doi: 10.1007/s00330-020-07541-x
pii: 10.1007/s00330-020-07541-x
doi:
Substances chimiques
Calcium
SY7Q814VUP
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4428-4437Références
Alshryda S, Shah A, Odak S, Al-Shryda J, Ilango B, Murali SR (2012) Acute fractures of the scaphoid bone: systematic review and meta-analysis. Surgeon 10:218–229
doi: 10.1016/j.surge.2012.03.004
Carpenter CR, Pines JM, Schuur JD, Muir M, Calfee RP, Raja AS (2014) Adult scaphoid fracture. Acad Emerg Med 21:101–121
doi: 10.1111/acem.12317
Fowler JR, Hughes TB (2015) Scaphoid fractures. Clin Sports Med 34:37–50
doi: 10.1016/j.csm.2014.09.011
Ko JH, Pet MA, Khouri JS, Hammert WC (2017) Management of scaphoid fractures. Plast Reconstr Surg 140:333e–346e
doi: 10.1097/PRS.0000000000003558
Yin ZG, Zhang JB, Gong KT (2015) Cost-effectiveness of diagnostic strategies for suspected scaphoid fractures. J Orthop Trauma 29:e245–e252
doi: 10.1097/BOT.0000000000000316
Ghadimi M, Sapra A (2020) Magnetic resonance imaging (MRI). ContraindicationsStatPearls, Treasure Island (FL)
Neubauer J, Benndorf M, Ehritt-Braun C et al (2018) Comparison of the diagnostic accuracy of cone beam computed tomography and radiography for scaphoid fractures. Sci Rep 8:3906
doi: 10.1038/s41598-018-22331-8
Booz C, Noske J, Albrecht MH et al (2019) Traumatic bone marrow edema of the calcaneus: evaluation of color-coded virtual non-calcium dual-energy CT in a multi-reader diagnostic accuracy study. Eur J Radiol 118:207–214
doi: 10.1016/j.ejrad.2019.07.023
Petritsch B, Kosmala A, Weng AM et al (2017) Vertebral compression fractures: third-generation dual-energy CT for detection of bone marrow edema at visual and quantitative analyses. Radiology 284:161–168
doi: 10.1148/radiol.2017162165
Mallinson PI, Coupal TM, McLaughlin PD, Nicolaou S, Munk PL, Ouellette HA (2016) Dual-energy CT for the musculoskeletal system. Radiology 281:690–707
doi: 10.1148/radiol.2016151109
Nicolaou S, Liang T, Murphy DT, Korzan JR, Ouellette H, Munk P (2012) Dual-energy CT: a promising new technique for assessment of the musculoskeletal system. AJR Am J Roentgenol 199:S78–S86
doi: 10.2214/AJR.12.9117
Pache G, Krauss B, Strohm P et al (2010) Dual-energy CT virtual noncalcium technique: detecting posttraumatic bone marrow lesions--feasibility study. Radiology 256:617–624
doi: 10.1148/radiol.10091230
Kaup M, Wichmann JL, Scholtz JE et al (2016) Dual-energy CT-based display of bone marrow edema in osteoporotic vertebral compression fractures: impact on diagnostic accuracy of radiologists with varying levels of experience in correlation to MR imaging. Radiology 280:510–519
doi: 10.1148/radiol.2016150472
Frellesen C, Azadegan M, Martin SS et al (2018) Dual-energy computed tomography-based display of bone marrow edema in incidental vertebral compression fractures: diagnostic accuracy and characterization in oncological patients undergoing routine staging computed tomography. Invest Radiol 53:409–416
doi: 10.1097/RLI.0000000000000458
Wang CK, Tsai JM, Chuang MT, Wang MT, Huang KY, Lin RM (2013) Bone marrow edema in vertebral compression fractures: detection with dual-energy CT. Radiology 269:525–533
doi: 10.1148/radiol.13122577
Kosmala A, Weng AM, Heidemeier A et al (2018) Multiple myeloma and dual-energy CT: diagnostic accuracy of virtual noncalcium technique for detection of bone marrow infiltration of the spine and pelvis. Radiology 286:205–213
doi: 10.1148/radiol.2017170281
Guggenberger R, Gnannt R, Hodler J et al (2012) Diagnostic performance of dual-energy CT for the detection of traumatic bone marrow lesions in the ankle: comparison with MR imaging. Radiology 264:164–173
doi: 10.1148/radiol.12112217
Reddy T, McLaughlin PD, Mallinson PI et al (2015) Detection of occult, undisplaced hip fractures with a dual-energy CT algorithm targeted to detection of bone marrow edema. Emerg Radiol 22:25–29
doi: 10.1007/s10140-014-1249-6
Bierry G, Venkatasamy A, Kremer S, Dosch JC, Dietemann JL (2014) Dual-energy CT in vertebral compression fractures: performance of visual and quantitative analysis for bone marrow edema demonstration with comparison to MRI. Skeletal Radiol 43:485–492
doi: 10.1007/s00256-013-1812-3
Pache G, Bulla S, Baumann T et al (2012) Dose reduction does not affect detection of bone marrow lesions with dual-energy CT virtual noncalcium technique. Acad Radiol 19:1539–1545
doi: 10.1016/j.acra.2012.08.006
Albrecht MH, Trommer J, Wichmann JL et al (2016) Comprehensive comparison of virtual monoenergetic and linearly blended reconstruction techniques in third-generation dual-source dual-energy computed tomography angiography of the thorax and abdomen. Invest Radiol 51:582–590
doi: 10.1097/RLI.0000000000000272
Muller FC, Borgesen H, Gosvig K et al (2019) Optimising dual-energy CT scan parameters for virtual non-calcium imaging of the bone marrow: a phantom study. Eur Radiol Exp 3:46
doi: 10.1186/s41747-019-0125-2
Cooney WP 3rd (2003) Scaphoid fractures: current treatments and techniques. Instr Course Lect 52:197–208
pubmed: 12690849
Genders TS, Spronk S, Stijnen T, Steyerberg EW, Lesaffre E, Hunink MG (2012) Methods for calculating sensitivity and specificity of clustered data: a tutorial. Radiology 265:910–916
doi: 10.1148/radiol.12120509
Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174
doi: 10.2307/2529310
Wesarg S, Kirschner M, Becker M, Erdt M, Kafchitsas K, Khan MF (2012) Dual-energy CT-based assessment of the trabecular bone in vertebrae. Methods Inf Med 51:398–405
doi: 10.3414/ME11-02-0034
Booz C, Noske J, Lenga L et al (2020) Color-coded virtual non-calcium dual-energy CT for the depiction of bone marrow edema in patients with acute knee trauma: a multireader diagnostic accuracy study. Eur Radiol 30:141–150
doi: 10.1007/s00330-019-06304-7
Dareez NM, Dahlslett KH, Engesland E, Lindland ES (2017) Scaphoid fracture: bone marrow edema detected with dual-energy CT virtual non-calcium images and confirmed with MRI. Skeletal Radiol 46:1753–1756
doi: 10.1007/s00256-017-2730-6
Albrecht MH, De Cecco CN, Schoepf UJ et al (2018) Dual-energy CT of the heart current and future status. Eur J Radiol 105:110–118
doi: 10.1016/j.ejrad.2018.05.028
Clementson M, Bjorkman A, Thomsen NOB (2020) Acute scaphoid fractures: guidelines for diagnosis and treatment. EFORT Open Rev 5:96–103
doi: 10.1302/2058-5241.5.190025
Schmitt R, Rosenthal H, Deutsche Gesellschaft fur Unfallchirurgie (2016) Imaging of scaphoid fractures according to the new S3 guidelines. Rofo 188:459–469
Boks SS, Vroegindeweij D, Koes BW, Hunink MG, Bierma-Zeinstra SM (2006) Follow-up of occult bone lesions detected at MR imaging: systematic review. Radiology 238:853–862
doi: 10.1148/radiol.2382050062
Sanders TG, Medynski MA, Feller JF, Lawhorn KW (2000) Bone contusion patterns of the knee at MR imaging: footprint of the mechanism of injury. Radiographics 20 spec no:S135–S151
doi: 10.1148/radiographics.20.suppl_1.g00oc19s135
Mandalia V, Fogg AJ, Chari R, Murray J, Beale A, Henson JH (2005) Bone bruising of the knee. Clin Radiol 60:627–636
doi: 10.1016/j.crad.2005.01.014
Barr MS, Anderson MW (2002) The knee: bone marrow abnormalities. Radiol Clin North Am 40:1109–1120
doi: 10.1016/S0033-8389(02)00051-9