Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE.
Accelerator
Cyclotron
DOTATATE
Gallium-68
PSMA-11
Solid target
Targetry
Journal
EJNMMI radiopharmacy and chemistry
ISSN: 2365-421X
Titre abrégé: EJNMMI Radiopharm Chem
Pays: England
ID NLM: 101714628
Informations de publication
Date de publication:
07 Jan 2021
07 Jan 2021
Historique:
received:
16
09
2020
accepted:
23
11
2020
entrez:
7
1
2021
pubmed:
8
1
2021
medline:
8
1
2021
Statut:
epublish
Résumé
With increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([ Enriched zinc-68 targets were irradiated at up to 80 µA with 13 MeV protons for 120 min; repeatedly producing up to 194 GBq (5.24 Ci) of purified gallium-68 in the form of [ We have developed a high-yielding, automated method for the production of very high amounts of [
Sections du résumé
BACKGROUND
BACKGROUND
With increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([
RESULTS
RESULTS
Enriched zinc-68 targets were irradiated at up to 80 µA with 13 MeV protons for 120 min; repeatedly producing up to 194 GBq (5.24 Ci) of purified gallium-68 in the form of [
CONCLUSIONS
CONCLUSIONS
We have developed a high-yielding, automated method for the production of very high amounts of [
Identifiants
pubmed: 33411034
doi: 10.1186/s41181-020-00114-9
pii: 10.1186/s41181-020-00114-9
pmc: PMC7790954
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1Références
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