Inequality in survival of people with head and neck cancer: Head and Neck 5000 cohort study.
Kaplan-Meier
cancer epidemiology
cohort study
head and neck cancer
inequality
survival
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
revised:
30
11
2020
received:
06
03
2020
accepted:
17
12
2020
pubmed:
9
1
2021
medline:
1
7
2021
entrez:
8
1
2021
Statut:
ppublish
Résumé
Explanations for socioeconomic inequalities in survival of head and neck cancer (HNC) patients have had limited attention and are not well understood. The UK Head and Neck 5000 prospective clinical cohort study was analyzed. Survival relating to measures of socioeconomic status was explored including area-based and individual factors. Three-year overall survival was determined using the Kaplan-Meier method. All-cause mortality was investigated via adjusted Cox Proportional Hazard models. A total of 3440 people were included. Three-year overall survival was 76.3% (95% CI 74.9, 77.7). Inequality in survival by deprivation category, highest education level, and financial concerns was explained by age, sex, health, and behavioral factors. None of the potential explanatory factors fully explained the inequality associated with annual household income or the proportion of income of benefits. These results support the interventions to address the financial issues within the wider care and support provided to HNC patients.
Sections du résumé
BACKGROUND
Explanations for socioeconomic inequalities in survival of head and neck cancer (HNC) patients have had limited attention and are not well understood.
METHODS
The UK Head and Neck 5000 prospective clinical cohort study was analyzed. Survival relating to measures of socioeconomic status was explored including area-based and individual factors. Three-year overall survival was determined using the Kaplan-Meier method. All-cause mortality was investigated via adjusted Cox Proportional Hazard models.
RESULTS
A total of 3440 people were included. Three-year overall survival was 76.3% (95% CI 74.9, 77.7). Inequality in survival by deprivation category, highest education level, and financial concerns was explained by age, sex, health, and behavioral factors. None of the potential explanatory factors fully explained the inequality associated with annual household income or the proportion of income of benefits.
CONCLUSION
These results support the interventions to address the financial issues within the wider care and support provided to HNC patients.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1252-1270Subventions
Organisme : Cancer Research UK
ID : C18281/A19169
Pays : United Kingdom
Organisme : Department of Health
ID : RP-PG-0707-10034
Pays : United Kingdom
Informations de copyright
© 2021 Wiley Periodicals LLC.
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