Meningococcal carriage among Hajj pilgrims, risk factors for carriage and records of vaccination: a study of pilgrims to Mecca.
Adolescent
Adult
Aged
Anti-Bacterial Agents
/ therapeutic use
Carrier State
/ diagnosis
Cross-Sectional Studies
Female
Humans
Islam
Male
Meningococcal Infections
/ microbiology
Meningococcal Vaccines
Middle Aged
Neisseria meningitidis
/ genetics
Patient Acceptance of Health Care
Prevalence
Risk Factors
Saudi Arabia
/ epidemiology
Self Medication
Serogroup
Travel
Vaccination
Vaccination Coverage
Young Adult
Neisseria meningitides
Hajj
antibiotic
meningococcal
pharyngeal carriage
vaccination
Journal
Tropical medicine & international health : TM & IH
ISSN: 1365-3156
Titre abrégé: Trop Med Int Health
Pays: England
ID NLM: 9610576
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
pubmed:
9
1
2021
medline:
31
7
2021
entrez:
8
1
2021
Statut:
ppublish
Résumé
The Saudi government requires that all pilgrims receive a quadrivalent meningococcal vaccine at least 10 days before the Hajj. We conducted a study to determine the uptake of meningococcal vaccine and antibiotic use. We also investigated risk factors of meningococcal carriage and carriage of Neisseria meningitidis pathogenic serogroups A, C, W and Y. A cross-sectional oropharyngeal carriage survey was conducted in 2973 Hajj pilgrims in September 2017. A real-time polymerase chain reaction (rt-PCR) assay was used to identify N. meningitidis from the oropharyngeal swabs. A questionnaire investigated potential risk factors for carriage of N. meningitidis. Two thousand two hundred forty nine oropharyngeal swabs were obtained. The overall prevalence of carriage of N. meningitidis was 4.6% (95% CI: 3.4%-6%). Carriage of pathogenic serogroups was not associated significantly with any of the meningococcal risk factors evaluated. 77% of pilgrims were vaccinated but 22.58 % said they were carrying unofficial vaccination cards. Carriage of serogroups A, C, W and Y was not significantly associated with any of the risk factors investigated. Almost a quarter of pilgrims were unlikely to have been vaccinated, highlighting a need to strengthen compliance with the current policy of vaccination to prevent meningococcal disease outbreaks during and after the Hajj.
Identifiants
pubmed: 33415766
doi: 10.1111/tmi.13546
pmc: PMC8049039
doi:
Substances chimiques
Anti-Bacterial Agents
0
Meningococcal Vaccines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
453-461Subventions
Organisme : Royal Embassy of Saudi Arabia Cultural Bureau in London, United Kingdom
Organisme : KAUST faculty baseline
ID : BAS/1/1020-01-01
Informations de copyright
© 2021 The Authors Tropical Medicine & International Health Published by John Wiley & Sons Ltd.
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