Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Type 2 Diabetes Risk in Postmenopausal Women.


Journal

Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975

Informations de publication

Date de publication:
03 2021
Historique:
received: 04 09 2020
accepted: 30 11 2020
pubmed: 10 1 2021
medline: 10 9 2021
entrez: 9 1 2021
Statut: ppublish

Résumé

The empirical dietary index for hyperinsulinemia (EDIH) and empirical dietary inflammatory pattern (EDIP) scores assess the insulinemic and inflammatory potentials of habitual dietary patterns, irrespective of the macronutrient content, and are based on plasma insulin response or inflammatory biomarkers, respectively. The glycemic index (GI) and glycemic load (GL) assess postprandial glycemic potential based on dietary carbohydrate content. We tested the hypothesis that dietary patterns promoting hyperinsulinemia, chronic inflammation, or hyperglycemia may influence type 2 diabetes risk. We calculated dietary scores from baseline (1993-1998) food frequency questionnaires among 73,495 postmenopausal women in the Women's Health Initiative, followed through March 2019. We used multivariable-adjusted Cox regression to estimate hazard ratios (HRs) and 95% CIs for type 2 diabetes risk. We also estimated multivariable-adjusted absolute risk of type 2 diabetes. During a median 13.3 years of follow-up, 11,009 incident cases of type 2 diabetes were diagnosed. Participants consuming the most hyperinsulinemic or proinflammatory dietary patterns experienced greater risk of type 2 diabetes; HRs (95% CI) comparing highest to lowest dietary index quintiles were EDIH 1.49 (1.32-1.68; Our findings in this diverse cohort of postmenopausal women suggest that lowering the insulinemic and inflammatory potentials of the diet may be more effective in preventing type 2 diabetes than focusing on glycemic foods.

Identifiants

pubmed: 33419931
pii: dc20-2216
doi: 10.2337/dc20-2216
pmc: PMC7896263
doi:

Substances chimiques

Dietary Carbohydrates 0

Banques de données

figshare
['10.2337/figshare.13312649']

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

707-714

Subventions

Organisme : NHLBI NIH HHS
ID : HHSN268201600002C
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600018C
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600003C
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600001C
Pays : United States
Organisme : CSRD VA
ID : I01 CX001737
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600004C
Pays : United States

Informations de copyright

© 2021 by the American Diabetes Association.

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Auteurs

Qi Jin (Q)

Interdisciplinary PhD Program in Nutrition, The Ohio State University, Columbus, OH.

Ni Shi (N)

The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH.

Desmond Aroke (D)

The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH.

Dong Hoon Lee (DH)

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.

Joshua J Joseph (JJ)

Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

Macarius Donneyong (M)

College of Pharmacy, The Ohio State University, Columbus, OH.

Darwin L Conwell (DL)

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

Phil A Hart (PA)

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

Xuehong Zhang (X)

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

Steven K Clinton (SK)

Interdisciplinary PhD Program in Nutrition, The Ohio State University, Columbus, OH.
The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH.
Division of Medical Oncology, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

Zobeida Cruz-Monserrate (Z)

Interdisciplinary PhD Program in Nutrition, The Ohio State University, Columbus, OH.
The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH.
Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

Theodore M Brasky (TM)

The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH.
Division of Medical Oncology, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

Rebecca Jackson (R)

Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

Lesley F Tinker (LF)

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.

Simin Liu (S)

Department of Epidemiology, Brown University, Providence, RI.

Lawrence S Phillips (LS)

Atlanta VA Health Care System, Decatur, GA.
Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA.

Aladdin H Shadyab (AH)

Department of Family Medicine and Public Health, School of Medicine, University of California San Diego, La Jolla, CA.

Rami Nassir (R)

Department of Pathology, School of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia.

Wei Bao (W)

Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA.

Fred K Tabung (FK)

Interdisciplinary PhD Program in Nutrition, The Ohio State University, Columbus, OH fred.tabung@osumc.edu.
The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH.
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Division of Medical Oncology, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.
Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH.

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