Healthy ageing for all? Comparisons of socioeconomic inequalities in health expectancies over two decades in the Cognitive Function and Ageing Studies I and II.


Journal

International journal of epidemiology
ISSN: 1464-3685
Titre abrégé: Int J Epidemiol
Pays: England
ID NLM: 7802871

Informations de publication

Date de publication:
09 07 2021
Historique:
accepted: 10 12 2020
pubmed: 10 1 2021
medline: 31 7 2021
entrez: 9 1 2021
Statut: ppublish

Résumé

Despite increasing life expectancy (LE), cross-sectional data show widening inequalities in disability-free LE (DFLE) by socioeconomic status (SES) in many countries. We use longitudinal data to better understand trends in DFLE and years independent (IndLE) by SES, and how underlying transitions contribute. The Cognitive Function and Ageing Studies (CFAS I and II) are large population-based studies of those aged ≥65 years in three English centres (Newcastle, Nottingham, Cambridgeshire), with baseline around 1991 (CFAS I, n = 7635) and 2011 (CFAS II, n = 7762) and 2-year follow-up. We defined disability as difficulty in activities of daily living (ADL), dependency by combining ADLs and cognition reflecting care required, and SES by area-level deprivation. Transitions between disability or dependency states and death were estimated from multistate models. Between 1991 and 2011, gains in DFLE at age 65 were greatest for the most advantaged men and women [men: 4.7 years, 95% confidence interval (95% CI) 3.3-6.2; women: 2.8 years, 95% CI 1.3-4.3]. Gains were due to the most advantaged women having a reduced risk of incident disability [relative risk ratio (RRR):0.7, 95% CI 0.5-0.8], whereas the most advantaged men had a greater likelihood of recovery (RRR: 1.8, 95% CI 1.0-3.2) and reduced disability-free mortality risk (RRR: 0.4, 95% CI 0.3-0.6]. Risk of death from disability decreased for least advantaged men (RRR: 0.7, 95% CI 0.6-0.9); least advantaged women showed little improvement in transitions. IndLE patterns across time were similar. Prevention should target the most disadvantaged areas, to narrow inequalities, with clear indication from the most advantaged that reduction in poor transitions is achievable.

Sections du résumé

BACKGROUND
Despite increasing life expectancy (LE), cross-sectional data show widening inequalities in disability-free LE (DFLE) by socioeconomic status (SES) in many countries. We use longitudinal data to better understand trends in DFLE and years independent (IndLE) by SES, and how underlying transitions contribute.
METHODS
The Cognitive Function and Ageing Studies (CFAS I and II) are large population-based studies of those aged ≥65 years in three English centres (Newcastle, Nottingham, Cambridgeshire), with baseline around 1991 (CFAS I, n = 7635) and 2011 (CFAS II, n = 7762) and 2-year follow-up. We defined disability as difficulty in activities of daily living (ADL), dependency by combining ADLs and cognition reflecting care required, and SES by area-level deprivation. Transitions between disability or dependency states and death were estimated from multistate models.
RESULTS
Between 1991 and 2011, gains in DFLE at age 65 were greatest for the most advantaged men and women [men: 4.7 years, 95% confidence interval (95% CI) 3.3-6.2; women: 2.8 years, 95% CI 1.3-4.3]. Gains were due to the most advantaged women having a reduced risk of incident disability [relative risk ratio (RRR):0.7, 95% CI 0.5-0.8], whereas the most advantaged men had a greater likelihood of recovery (RRR: 1.8, 95% CI 1.0-3.2) and reduced disability-free mortality risk (RRR: 0.4, 95% CI 0.3-0.6]. Risk of death from disability decreased for least advantaged men (RRR: 0.7, 95% CI 0.6-0.9); least advantaged women showed little improvement in transitions. IndLE patterns across time were similar.
CONCLUSIONS
Prevention should target the most disadvantaged areas, to narrow inequalities, with clear indication from the most advantaged that reduction in poor transitions is achievable.

Identifiants

pubmed: 33421052
pii: 6076702
doi: 10.1093/ije/dyaa271
pmc: PMC8271204
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

841-851

Subventions

Organisme : Department of Health
ID : PR-PRU-1217-21502
Pays : United Kingdom
Organisme : The Dunhill Medical Trust
ID : RPGF1806/44
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0601022
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P012299/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G9901400
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K02325X/1
Pays : United Kingdom

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the International Epidemiological Association.

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Auteurs

Holly Q Bennett (HQ)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

Andrew Kingston (A)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

Gemma Spiers (G)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

Louise Robinson (L)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

Lynne Corner (L)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

Clare Bambra (C)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

Carol Brayne (C)

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Fiona E Matthews (FE)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

Carol Jagger (C)

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

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Classifications MeSH