Sodium molybdate induces heterophil extracellular traps formation in chicken.
Animals
Chickens
/ immunology
Extracellular Traps
/ drug effects
Glucose Transporter Type 1
/ immunology
Glucose Transporter Type 4
/ immunology
Glycolysis
Immunity, Innate
/ drug effects
MAP Kinase Signaling System
/ drug effects
Molybdenum
/ toxicity
NADPH Oxidases
/ immunology
Neutrophils
/ drug effects
Reactive Oxygen Species
/ immunology
Chicken
Glycolysis
Heterophils extracellular traps
ROS
Sodium molybdate
Journal
Ecotoxicology and environmental safety
ISSN: 1090-2414
Titre abrégé: Ecotoxicol Environ Saf
Pays: Netherlands
ID NLM: 7805381
Informations de publication
Date de publication:
01 Mar 2021
01 Mar 2021
Historique:
received:
12
08
2020
revised:
27
12
2020
accepted:
29
12
2020
pubmed:
10
1
2021
medline:
2
2
2021
entrez:
9
1
2021
Statut:
ppublish
Résumé
Molybdenum (Mo) is not only an important rare metal that is widely used in industrial production but also an essential trace element for plants and animals. Nevertheless, in Mo polluted areas, excess Mo intake will not only cause gout in humans but also cause diarrhea in livestock and growth inhibition of chickens. Heterophils extracellular traps (HETs) are an important way to clear pathogens in the innate immune system of the chicken. However, the effects of Mo on the innate immune responses of HETs formation in chicken, and the mechanism undergoing this phenomenon remain unknown. In the study, we firstly aim to investigate the effects of sodium molybdate (Na
Identifiants
pubmed: 33421725
pii: S0147-6513(20)31722-X
doi: 10.1016/j.ecoenv.2020.111886
pii:
doi:
Substances chimiques
Glucose Transporter Type 1
0
Glucose Transporter Type 4
0
Reactive Oxygen Species
0
Molybdenum
81AH48963U
sodium molybdate(VI)
948QAQ08I1
NADPH Oxidases
EC 1.6.3.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
111886Informations de copyright
Copyright © 2021. Published by Elsevier Inc.