[Stereotactic body radiotherapy for locally advanced pancreatic cancer: A systemic review].

Radiothérapie stéréotaxique dans le cancer du pancréas localement avancé : revue de la littérature.
Adénocarcinome du pancréas Contrôle local Local control Localement avancé Locally advanced Pancreatic adenocarcinoma Radiation therapy Radiothérapie SBRT Stéréotaxie

Journal

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
ISSN: 1769-6658
Titre abrégé: Cancer Radiother
Pays: France
ID NLM: 9711272

Informations de publication

Date de publication:
May 2021
Historique:
received: 24 05 2020
revised: 02 08 2020
accepted: 06 08 2020
pubmed: 12 1 2021
medline: 14 5 2021
entrez: 11 1 2021
Statut: ppublish

Résumé

Stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC) is an emerging treatment option. Most studies showed local control of approximately 75% with no evidence of improved overall survival. Gastrointestinal toxicities could be significant, ranging up to 22% for acute toxicities≥grade 3+ and 44% for late toxicities≥grade 3+. Currently, no standardized guidelines for treatment and management scheme. We conducted a systemic review of published prospective and retrospective trials to evaluate the efficacy, safety, technical data, and discuss future directions.

Identifiants

pubmed: 33423968
pii: S1278-3218(20)30338-3
doi: 10.1016/j.canrad.2020.08.047
pii:
doi:

Types de publication

Journal Article Systematic Review

Langues

fre

Sous-ensembles de citation

IM

Pagination

283-295

Informations de copyright

Copyright © 2021 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.

Auteurs

M Tonneau (M)

Département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Combemale, 59020 Lille cedex, France. Electronic address: marion.tonneau@gmail.com.

T Lacornerie (T)

Service de physique médicale, centre Oscar-Lambret, 3, rue Combemale, 59020 Lille cedex, France.

X Mirabel (X)

Département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Combemale, 59020 Lille cedex, France.

D Pasquier (D)

Département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Combemale, 59020 Lille cedex, France; Centre de recherche en informatique, signal et automatique de Lille, UMR CNRS 9189, université de Lille, M3, avenue Carl-Gauss, 59650 Villeneuve-d'Ascq, France.

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Classifications MeSH