A Rare Case of Plasma Cell Granuloma.
Journal
Case reports in dentistry
ISSN: 2090-6447
Titre abrégé: Case Rep Dent
Pays: Egypt
ID NLM: 101573242
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
06
2020
revised:
07
12
2020
accepted:
17
12
2020
entrez:
11
1
2021
pubmed:
12
1
2021
medline:
12
1
2021
Statut:
epublish
Résumé
Plasma cell granulomas (PCGs) or inflammatory pseudotumors are nonneoplastic lesions that consist of predominantly antibody-secreting plasma cells and innate immune cells such as neutrophils, macrophages, and eosinophils. Unlike in multiple myeloma, the plasma cells are polyclonal and present in a spindly fibroblast-rich stromal background. These lesions mainly occur in the lungs; however, they can arise in other organs. PCGs from the gingiva are extremely rare, and a proper diagnosis is crucial to treat these patients further. These tumors have an increased number of plasma cells that are immunoreactive with CD138 and are polyclonal for kappa and lambda light chains, confirming these proliferations' nonneoplastic nature. Surgical resection with clear margins, when possible, is the primary choice of treatment. Radiation and anti-inflammatory steroid therapy are other therapeutic approaches. Critical and careful examination by a pathologist is necessary to rule out plasma cell neoplasms. Here, we report a rare occurrence of gingival PCG in an elderly male.
Identifiants
pubmed: 33425399
doi: 10.1155/2020/8861918
pmc: PMC7781719
doi:
Types de publication
Case Reports
Langues
eng
Pagination
8861918Informations de copyright
Copyright © 2020 Archana P. Kanteti et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.
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