Impaired host response and the presence of
Human Metabolism
Microbiology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
22 Jan 2021
22 Jan 2021
Historique:
received:
22
09
2020
revised:
28
10
2020
accepted:
10
12
2020
entrez:
11
1
2021
pubmed:
12
1
2021
medline:
12
1
2021
Statut:
epublish
Résumé
Type II diabetes (T2D) affects over 10% of the US population and is a growing disease worldwide that manifests with numerous comorbidities and defects in inflammation. This dysbiotic host response allows for infection of the host by numerous microorganisms. In the course of T2D disease, individuals can develop chronic infections including foot ulcers and periodontitis, which lead to further complications and opportunistic infections in multiple body sites. In this study, we investigated the serum of healthy subjects and patients with T2D with (T2DP) or without periodontitis for both microbiome signatures in addition to cytokine profiles. Surprisingly, we detected the presence of
Identifiants
pubmed: 33426512
doi: 10.1016/j.isci.2020.101941
pii: S2589-0042(20)31138-X
pmc: PMC7779772
doi:
Types de publication
Journal Article
Langues
eng
Pagination
101941Subventions
Organisme : NIDCR NIH HHS
ID : K23 DE018917
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM103430
Pays : United States
Organisme : NIDCR NIH HHS
ID : R00 DE023584
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE027958
Pays : United States
Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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