Absence of a vergence-mediated vestibulo-ocular reflex gain increase does not preclude adaptation.

Adaptation, Physiological Head Movements Humans Reflex, Vestibulo-Ocular
Vestibular neuritis vestibular adaptation vestibuloocular reflex

Journal

Journal of vestibular research : equilibrium & orientation
ISSN: 1878-6464
Titre abrégé: J Vestib Res
Pays: Netherlands
ID NLM: 9104163

Informations de publication

Date de publication:
2021
Historique:
pubmed: 12 1 2021
medline: 29 10 2021
entrez: 11 1 2021
Statut: ppublish

Résumé

The gain (eye-velocity/head-velocity) of the angular vestibuloocular reflex (aVOR) during head impulses can be increased while viewing near-targets and when exposed to unilateral, incremental retinal image velocity error signals. It is not clear however, whether the tonic or phasic vestibular pathways mediate these gain increases. Determine whether a shared pathway is responsible for gain enhancement between vergence and adaptation of aVOR gain in patients with unilateral vestibular hypofunction (UVH). 20 patients with UVH were examined for change in aVOR gain during a vergence task and after 15-minutes of ipsilesional incremental VOR adaptation (uIVA) using StableEyes (a device that controls a laser target as a function of head velocity) during horizontal passive head impulses. A 5 % aVOR gain increase was defined as the threshold for significant change. 11/20 patients had >5% vergence-mediated gain increase during ipsi-lesional impulses. For uIVA, 10/20 patients had >5% ipsi-lesional gain increase. There was no correlation between the vergence-mediated gain increase and gain increase after uIVA training. Vergence-enhanced and uIVA training gain increases are mediated by separate mechanisms and/or vestibular pathways (tonic/phasic). The ability to increase the aVOR gain during vergence is not prognostic for successful adaptation training.

Sections du résumé

BACKGROUND
The gain (eye-velocity/head-velocity) of the angular vestibuloocular reflex (aVOR) during head impulses can be increased while viewing near-targets and when exposed to unilateral, incremental retinal image velocity error signals. It is not clear however, whether the tonic or phasic vestibular pathways mediate these gain increases.
OBJECTIVE
Determine whether a shared pathway is responsible for gain enhancement between vergence and adaptation of aVOR gain in patients with unilateral vestibular hypofunction (UVH).
MATERIAL AND METHODS
20 patients with UVH were examined for change in aVOR gain during a vergence task and after 15-minutes of ipsilesional incremental VOR adaptation (uIVA) using StableEyes (a device that controls a laser target as a function of head velocity) during horizontal passive head impulses. A 5 % aVOR gain increase was defined as the threshold for significant change.
RESULTS
11/20 patients had >5% vergence-mediated gain increase during ipsi-lesional impulses. For uIVA, 10/20 patients had >5% ipsi-lesional gain increase. There was no correlation between the vergence-mediated gain increase and gain increase after uIVA training.
CONCLUSION
Vergence-enhanced and uIVA training gain increases are mediated by separate mechanisms and/or vestibular pathways (tonic/phasic). The ability to increase the aVOR gain during vergence is not prognostic for successful adaptation training.

Identifiants

DOI: 10.3233/VES-201560 PMID: 33427708
pubmed: 33427708
pii: VES201560
doi: 10.3233/VES-201560
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109-117

Auteurs

Béla Büki (B)

Department of Otolaryngology, Karl Landsteiner University Hospital Krems, Krems an der Donau, Austria.

László T Tamás (LT)

Department of Otolaryngology, Petz Aladár Teaching Hospital, Györ, Hungary.

Christopher J Todd (CJ)

Balance and Vision Laboratory, Neuroscience Research Australia, Sydney, NSW, Australia.

Michael C Schubert (MC)

Laboratory of Vestibular NeuroAdaptation, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland.
Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland.

Americo A Migliaccio (AA)

Balance and Vision Laboratory, Neuroscience Research Australia, Sydney, NSW, Australia.
Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA.
School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.

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Classifications MeSH

questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Adaptation physiologique › Absence of a vergence-mediated...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Mouvement › Mouvements de la tête › Absence of a vergence-mediated...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Absence of a vergence-mediated...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Réflexe › Réflexe vestibulo-oculaire › Absence of a vergence-mediated...