An investigation of calcium carbonate core-shell particles for incorporation of

Alpha Particles Animals Calcium Carbonate Nuclear Family Radioisotopes Rats Rats, Wistar
Actinium Alpha therapy Calcium carbonate Core-shell particles Daughter isotopes Radiolabeling Radionuclide retention SPECT in vivo biodistribution

Journal

Journal of controlled release : official journal of the Controlled Release Society
ISSN: 1873-4995
Titre abrégé: J Control Release
Pays: Netherlands
ID NLM: 8607908

Informations de publication

Date de publication:
10 02 2021
Historique:
received: 04 09 2020
revised: 04 12 2020
accepted: 04 01 2021
pubmed: 12 1 2021
medline: 8 7 2021
entrez: 11 1 2021
Statut: ppublish

Résumé

Alpha therapy provides an outstanding prospect in the treatment of recalcitrant and micrometastatic cancers. However, side effects on the normal tissues and organs (especially, kidneys) due to the release of daughter isotopes from α-emitters remain a bottleneck. In this work, calcium carbonate core-shell particles of different sizes were considered as isotope carriers for encapsulation of

Identifiants

DOI: 10.1016/j.jconrel.2021.01.008 PMID: 33428985
pubmed: 33428985
pii: S0168-3659(21)00017-1
doi: 10.1016/j.jconrel.2021.01.008
pii:
doi:

Substances chimiques

Radioisotopes 0
Calcium Carbonate H0G9379FGK

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

726-737

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Albert R Muslimov (AR)

Granov Russian Research Center of Radiology & Surgical Technologies, Leningradskaya Street 70 Pesochny, Saint-Petersburg 197758, Russian Federation; Nanobiotechnology Laboratory, St. Petersburg Academic University, 194021 St. Petersburg, Russian Federation; Peter The Great St. Petersburg Polytechnic University, Polytechnicheskaya 29, 195251 St. Petersburg, Russian Federation.

Dmitrii Antuganov (D)

Granov Russian Research Center of Radiology & Surgical Technologies, Leningradskaya Street 70 Pesochny, Saint-Petersburg 197758, Russian Federation.

Yana V Tarakanchikova (YV)

Granov Russian Research Center of Radiology & Surgical Technologies, Leningradskaya Street 70 Pesochny, Saint-Petersburg 197758, Russian Federation; Nanobiotechnology Laboratory, St. Petersburg Academic University, 194021 St. Petersburg, Russian Federation.

Timofey E Karpov (TE)

Granov Russian Research Center of Radiology & Surgical Technologies, Leningradskaya Street 70 Pesochny, Saint-Petersburg 197758, Russian Federation; Peter The Great St. Petersburg Polytechnic University, Polytechnicheskaya 29, 195251 St. Petersburg, Russian Federation.

Mikhail V Zhukov (MV)

Department of Physics and Engineering, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russian Federation.

Mikhail V Zyuzin (MV)

Granov Russian Research Center of Radiology & Surgical Technologies, Leningradskaya Street 70 Pesochny, Saint-Petersburg 197758, Russian Federation; Department of Physics and Engineering, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russian Federation. Electronic address: mikhail.zyuzin@metalab.ifmo.ru.

Alexander S Timin (AS)

Granov Russian Research Center of Radiology & Surgical Technologies, Leningradskaya Street 70 Pesochny, Saint-Petersburg 197758, Russian Federation; Peter The Great St. Petersburg Polytechnic University, Polytechnicheskaya 29, 195251 St. Petersburg, Russian Federation; Research School of Chemical and Biomedical Engineering, National Research Tomsk Polytechnic University, Lenin Avenue 30, Tomsk 634050, Russian Federation. Electronic address: timin@tpu.ru.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiques › Rayonnement › Rayonnement ionisant › Particules alpha › An investigation of calcium carbonate...
questionsmedicales.fr › Eucaryotes › Animaux › An investigation of calcium carbonate...
questionsmedicales.fr › Produits chimiques inorganiques › Minéraux › Carbonate de calcium › An investigation of calcium carbonate...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › Caractéristiques familiales › Structure familiale › Famille nucléaire › An investigation of calcium carbonate...
questionsmedicales.fr › Produits chimiques inorganiques › Isotopes › Radio-isotopes › An investigation of calcium carbonate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › An investigation of calcium carbonate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › An investigation of calcium carbonate...