Polymorphisms in Pepsinogen C and miRNA Genes Associate with High Serum Pepsinogen II in Gastric Cancer Patients.
Helicobacter pylori
PGC
RNAs
gastric cancer
polymorphisms
serum pepsinogen II
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
07 Jan 2021
07 Jan 2021
Historique:
received:
18
11
2020
accepted:
03
01
2021
entrez:
12
1
2021
pubmed:
13
1
2021
medline:
13
1
2021
Statut:
epublish
Résumé
Pepsinogen (PG) II (PGII) is a serological marker used to estimate the risk of gastric cancer but how PGII expression is regulated is largely unknown. It has been suggested that PGII expression, from the Serum levels of PGI and PGII were determined in 80 patients with gastric cancer and persons at risk for gastric cancer (74 first-degree relatives of patients, 62 patients with autoimmune chronic atrophic gastritis, and 2 patients with dysplasia), with and without PGII levels were significantly higher in patients with gastric cancer, and in those with Serum PGII levels depend in part on an interaction between
Sections du résumé
BACKGROUND
BACKGROUND
Pepsinogen (PG) II (PGII) is a serological marker used to estimate the risk of gastric cancer but how PGII expression is regulated is largely unknown. It has been suggested that PGII expression, from the
METHODS
METHODS
Serum levels of PGI and PGII were determined in 80 patients with gastric cancer and persons at risk for gastric cancer (74 first-degree relatives of patients, 62 patients with autoimmune chronic atrophic gastritis, and 2 patients with dysplasia), with and without
RESULTS
RESULTS
PGII levels were significantly higher in patients with gastric cancer, and in those with
CONCLUSIONS
CONCLUSIONS
Serum PGII levels depend in part on an interaction between
Identifiants
pubmed: 33430456
pii: microorganisms9010126
doi: 10.3390/microorganisms9010126
pmc: PMC7827830
pii:
doi:
Types de publication
Journal Article
Langues
eng
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