BRAFV600E
HRAS mutations
JAK2V617F
Polycythemia vera
hairy cell leukemia
thyroid adenoma
Journal
Tumori
ISSN: 2038-2529
Titre abrégé: Tumori
Pays: United States
ID NLM: 0111356
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
pubmed:
13
1
2021
medline:
15
12
2021
entrez:
12
1
2021
Statut:
ppublish
Résumé
Polycythemia vera (PV) is one of the Philadelphia-negative myeloproliferative neoplasms (MPN), characterized by a pan-myelosis with an erythroid-predominant proliferation mainly driven by somatic Here we report a molecular diagnostic challenge in a woman with a concomitant diagnosis of In the age of molecular and precision medicine, this case underlines the importance of integrating molecular results with clinical, radiologic, cytologic, and histopathologic investigations.
Sections du résumé
BACKGROUND
BACKGROUND
Polycythemia vera (PV) is one of the Philadelphia-negative myeloproliferative neoplasms (MPN), characterized by a pan-myelosis with an erythroid-predominant proliferation mainly driven by somatic
CASE PRESENTATION
METHODS
Here we report a molecular diagnostic challenge in a woman with a concomitant diagnosis of
CONCLUSION
CONCLUSIONS
In the age of molecular and precision medicine, this case underlines the importance of integrating molecular results with clinical, radiologic, cytologic, and histopathologic investigations.
Identifiants
pubmed: 33430710
doi: 10.1177/0300891620986621
doi:
Substances chimiques
Protein Kinase Inhibitors
0
BRAF protein, human
EC 2.7.11.1
Proto-Oncogene Proteins B-raf
EC 2.7.11.1
HRAS protein, human
EC 3.6.5.2
Proto-Oncogene Proteins p21(ras)
EC 3.6.5.2
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM