Progress in cardiovascular bioprinting.
3D printing
bioprinting
cardiovascular
heart tissue
tissue engineering
Journal
Artificial organs
ISSN: 1525-1594
Titre abrégé: Artif Organs
Pays: United States
ID NLM: 7802778
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
revised:
13
12
2020
received:
06
10
2020
accepted:
04
01
2021
pubmed:
13
1
2021
medline:
15
12
2021
entrez:
12
1
2021
Statut:
ppublish
Résumé
Cardiovascular disease has been the leading cause of death globally for the past 15 years. Following a major cardiac disease episode, the ideal treatment would be the replacement of the damaged tissue, due to the limited regenerative capacity of cardiac tissues. However, we suffer from a chronic organ donor shortage which causes approximately 20 people to die each day waiting to receive an organ. Bioprinting of tissues and organs can potentially alleviate this burden by fabricating low cost tissue and organ replacements for cardiac patients. Clinical adoption of bioprinting in cardiovascular medicine is currently limited by the lack of systematic demonstration of its effectiveness, high costs, and the complexity of the workflow. Here, we give a concise review of progress in cardiovascular bioprinting and its components. We further discuss the challenges and future prospects of cardiovascular bioprinting in clinical applications.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
652-664Informations de copyright
© 2021 International Center for Artificial Organs and Transplantation and Wiley Periodicals LLC.
Références
The top 10 causes of death. Available from https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
Birla R. Introduction to tissue engineering: applications and challenges. Hoboken, NJ: Wiley, 2014.
Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics-2019 update: a report from the American Heart Association [published correction appears in Circulation. 2020;141(2):e33]. Circulation. 2019;139(10):e56-e528. https://doi.org/10.1161/CIR.0000000000000659.
Organ Donation Statistics. 2020. Available from https://www.organdonor.gov/statistics-stories/statistics.html
Heart Disease and Stroke Statistics-2019 update: a report. Available from https://www.ahajournals.org/doi/10.1161/CIR.0000000000000659
Vijayavenkataraman S. Nerve guide conduits for peripheral nerve injury repair: a review on design, materials, and fabrication methods. Acta Biomater. 2020;106:54-69. https://doi.org/10.1016/j.actbio.2020.02.003.
Fakhruddin K, Razak SIA, Nayan NHM, Kadir MRA. 3D Bioprinting of a Tissue Engineered Human Heart. In: Dewi D, Hau Y, Khudzari A, Muhamad I, Supriyanto E eds. Cardiovascular Engineering. Series in BioEngineering. Singapore: Springer, 2020. https://doi.org/10.1007/978-981-10-8405-8_11.
Tucker NR, Chaffin M, Fleming SJ, Hall AW, Parsons VA, Bedi KC Jr, et al. Transcriptional and cellular diversity of the human heart. Circulation. 2020;142(5):466-82. https://doi.org/10.1161/CIRCULATIONAHA.119.045401
Giannopoulos AA, Mitsouras D, Yoo SJ, Liu PP, Chatzizisis YS, Rybicki FJ. Applications of 3D printing in cardiovascular diseases. Nat Rev Cardiol. 2016;13(12):701-18. https://doi.org/10.1038/nrcardio.2016.170.
Sanjairaj V, Kannan S, Cao T, Fuh JYH, Sriram G, Lu WF. 3D-printed PCL/PPy conductive scaffolds as three-dimensional porous nerve guide conduits for peripheral nerve injury repair. Front Bioeng Biotech. 2019;7:266. https://doi.org/10.3389/fbioe.2019.00266.
Puluca N, Lee S, Doppler S, Münsterer A, Dreßen M, Krane M, et al. Bioprinting approaches to engineering vascularized 3D cardiac tissues. Curr Cardiol Rep. 2019;21(9):90. https://doi.org/10.1007/s11886-019-1179-8.
Smith CM, Stone AL, Parkhill RL, Stewart RL, Simpkins MW, Kachurin AM, et al. Three-dimensional bioassembly tool for generating viable tissue-engineered constructs. Tissue Eng. 2004;10(9-10):1566-76. https://doi.org/10.1089/ten.2004.10.1566.
Visser J, Peters B, Burger TJ, Boomstra J, Dhert WJ, Melchels FP, et al. Biofabrication of multi-material anatomically shaped tissue constructs. Biofabrication. 2013;5(3):035007. https://doi.org/10.1088/1758-5082/5/3/035007.
Liu W, Zhang YS, Heinrich MA, De Ferrari F, Jang HL, Bakht SM, et al. Adv Mater. 2017;29(3): https://doi.org/10.1002/adma.201604630.
Xu T, Kincaid H, Atala A, Yoo JJ. High-Throughput Production of Single-Cell Microparticles Using an Inkjet Printing Technology. J Manuf Sci Eng. 2008;130(2): https://doi.org/10.1115/1.2903064.
Cui X, Boland T. Human microvasculature fabrication using thermal inkjet printing technology. Biomaterials. 2009;30(31):6221-7. https://doi.org/10.1016/j.biomaterials.2009.07.056.
Odde DJ, Renn MJ. Laser-guided direct writing for applications in biotechnology. Trends Biotechnol. 1999;17(10):385-9. https://doi.org/10.1016/s0167-7799(99)01355-4.
Koch L, Deiwick A, Franke A, Schwanke K, Haverich A, Zweigerdt R, et al. Laser bioprinting of human induced pluripotent stem cells-the effect of printing and biomaterials on cell survival, pluripotency, and differentiation. Biofabrication. 2018;10(3):035005. https://doi.org/10.1088/1758-5090/aab981.
Duan B. State-of-the-Art Review of 3D Bioprinting for Cardiovascular Tissue Engineering. Ann Biomed Eng. 2017;45(1):195-209. https://doi.org/10.1007/s10439-016-1607-5.
Gardin C, Ferroni L, Latremouille C, Chachques JC, Mitrečić D, Zavan B. Recent applications of three dimensional printing in cardiovascular medicine. Cells. 2020;9(3):742. https://doi.org/10.3390/cells9030742.
Wang Z, Lee SJ, Cheng HJ, Yoo JJ, Atala A. 3D bioprinted functional and contractile cardiac tissue constructs. Acta Biomater. 2018;70:48-56. https://doi.org/10.1016/j.actbio.2018.02.007.
Jang J, Park HJ, Kim SW, Kim H, Park JY, Na SJ, et al. 3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair. Biomaterials. 2017;112:264-74. https://doi.org/10.1016/j.biomaterials.2016.10.026.
Das S, Kim SW, Choi YJ, Lee S, Lee SH, Kong JS, et al. Decellularized extracellular matrix bioinks and the external stimuli to enhance cardiac tissue development in vitro. Acta Biomater. 2019;95:188-200. https://doi.org/10.1016/j.actbio.2019.04.026.
Xu T, Baicu C, Aho M, Zile M, Boland T. Fabrication and characterization of bio-engineered cardiac pseudo tissues. Biofabrication. 2009;1(3):035001. https://doi.org/10.1088/1758-5082/1/3/035001.
Gruene M, Deiwick A, Koch L, Schlie S, Unger C, Hofmann N, et al. Laser printing of stem cells for biofabrication of scaffold-free autologous grafts. Tissue Eng Part C Methods. 2011;17(1):79-87. https://doi.org/10.1089/ten.TEC.2010.0359.
Chimene D, Lennox KK, Kaunas RR, Gaharwar AK. Advanced bioinks for 3D printing: a materials science perspective. Ann Biomed Eng. 2016;44(6):2090-102. https://doi.org/10.1007/s10439-016-1638-y.
Qasim M, Haq F, Kang MH, Kim JH. 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration. Int J Nanomedicine. 2019;14:1311-33. https://doi.org/10.2147/IJN.S189587.
Heid S, Boccaccini AR. Advancing bioinks for 3D bioprinting using reactive fillers: a review. Acta Biomater. 2020;113:1-22. https://doi.org/10.1016/j.actbio.2020.06.040.
Hospodiuk M, Dey M, Sosnoski D, Ozbolat IT. The bioink: a comprehensive review on bioprintable materials. Biotechnol Adv. 2017;35(2):217-39. https://doi.org/10.1016/j.biotechadv.2016.12.006.
Datta P, Ayan B, Ozbolat IT. Bioprinting for vascular and vascularized tissue biofabrication. Acta Biomater. 2017;51:1-20. https://doi.org/10.1016/j.actbio.2017.01.035.
Cui H, Nowicki M, Fisher JP, Zhang LG. 3D bioprinting for organ regeneration. Adv Healthc Mater. 2017;6(1):1601118. https://doi.org/10.1002/adhm.201601118.
Moldovan NI. Progress in scaffold-free bioprinting for cardiovascular medicine. J Cell Mol Med. 2018;22(6):2964-9. https://doi.org/10.1111/jcmm.13598.
Yu Y, Moncal KK, Li J, Peng W, Rivero I, Martin JA, et al. Three-dimensional bioprinting using self-assembling scalable scaffold-free "tissue strands" as a new bioink. Sci Rep. 2016;6:28714. https://doi.org/10.1038/srep28714.
Mosadegh B, Xiong G, Dunham S, Min JK. Current progress in 3D printing for cardiovascular tissue engineering. Biomed Mater. 2015;10(3):034002. https://doi.org/10.1088/1748-6041/10/3/034002.
Nikolova MP, Chavali MS. Recent advances in biomaterials for 3D scaffolds: a review. Bioact Mater. 2019;4:271-92. https://doi.org/10.1016/j.bioactmat.2019.10.005.
Gungor-Ozkerim PS, Inci I, Zhang YS, Khademhosseini A, Dokmeci MR. Bioinks for 3D bioprinting: an overview. Biomater Sci. 2018;6(5):915-46. https://doi.org/10.1039/c7bm00765e.
Peña B, Laughter M, Jett S, Rowland TJ, Taylor MRG, Mestroni L, et al. Injectable hydrogels for cardiac tissue engineering. Macromol Biosci. 2018;18(6):e1800079. https://doi.org/10.1002/mabi.201800079.
Tang-Quan KR, Mehta NA, Sampaio LC, Taylor DA. Whole cardiac tissue bioscaffolds. Adv Exp Med Biol. 2018;1098:85-114. https://doi.org/10.1007/978-3-319-97421-7_5.
Alagarsamy KN, Yan W, Srivastava A, Desiderio V, Dhingra S. Application of injectable hydrogels for cardiac stem cell therapy and tissue engineering. Rev Cardiovasc Med. 2019;20(4):221-30. https://doi.org/10.31083/j.rcm.2019.04.534.
Ovsianikov A, Khademhosseini A, Mironov V. The synergy of scaffold-based and scaffold-free tissue engineering strategies. Trends Biotechnol. 2018;36(4):348-57. https://doi.org/10.1016/j.tibtech.2018.01.005.
Hölzl K, Lin S, Tytgat L, Van Vlierberghe S, Gu L, Ovsianikov A. Bioink properties before, during and after 3D bioprinting. Biofabrication. 2016;8(3):032002. https://doi.org/10.1088/1758-5090/8/3/032002.
Axpe E, Oyen ML. Applications of alginate-based bioinks in 3d bioprinting. Int J Mol Sci. 2016;17(12):1976. https://doi.org/10.3390/ijms17121976.
Faramarzi N, Yazdi IK, Nabavinia M, Gemma A, Fanelli A, Caizzone A, et al. Patient-specific bioinks for 3d bioprinting of tissue engineering scaffolds. Adv Healthc Mater. 2018;7(11):e1701347. https://doi.org/10.1002/adhm.201701347.
Gopinathan J, Noh I. Recent trends in bioinks for 3D printing. Biomater Res. 2018;22:11. https://doi.org/10.1186/s40824-018-0122-1.
Donderwinkel I, van Hest JCM, Cameron NR. Bio-inks for 3D bioprinting: recent advances and future prospects. Polym Chem. 2017;8:4451-71.
Heinrich MA, Liu W, Jimenez A, Yang J, Akpek A, Liu X, et al. 3D bioprinting: from benches to translational applications. Small. 2019;15(23):e1805510. https://doi.org/10.1002/smll.201805510.
Valot L, Martinez J, Mehdi A, Subra G. Chemical insights into bioinks for 3D printing. Chem Soc Rev. 2019;48(15):4049-86. https://doi.org/10.1039/c7cs00718c.
Freeman S, Ramos R, Alexis Chando P, Zhou L, Reeser K, Jin S, et al. A bioink blend for rotary 3D bioprinting tissue engineered small-diameter vascular constructs. Acta Biomater. 2019;95:152-64. https://doi.org/10.1016/j.actbio.2019.06.052.
Salah M, Tayebi L, Moharamzadeh K, Naini FB. Three-dimensional bio-printing and bone tissue engineering: technical innovations and potential applications in maxillofacial reconstructive surgery. Maxillofac Plast Reconstr Surg. 2020;42(1):18. https://doi.org/10.1186/s40902-020-00263-6.
Tallawi M, Rosellini E, Barbani N, Cascone MG, Rai R, Saint-Pierre G, et al. Strategies for the chemical and biological functionalization of scaffolds for cardiac tissue engineering: a review. J R Soc Interface. 2015;12(108):20150254. https://doi.org/10.1098/rsif.2015.0254.
Asghari F, Samiei M, Adibkia K, Akbarzadeh A, Davaran S. Biodegradable and biocompatible polymers for tissue engineering application: a review. Artif Cells Nanomed Biotechnol. 2017;45(2):185-92. https://doi.org/10.3109/21691401.2016.1146731.
Ashtari K, Nazari H, Ko H, Tebon P, Akhshik M, Akbari M, et al. Electrically conductive nanomaterials for cardiac tissue engineering. Adv Drug Deliv Rev. 2019;144:162-79. https://doi.org/10.1016/j.addr.2019.06.001.
Baei P, Jalili-Firoozinezhad S, Rajabi-Zeleti S, Tafazzoli-Shadpour M, Baharvand H, Aghdami N. Electrically conductive gold nanoparticle-chitosan thermosensitive hydrogels for cardiac tissue engineering. Mater Sci Eng C Mater Biol Appl. 2016;63:131-41. https://doi.org/10.1016/j.msec.2016.02.056.
Shokraei N, Asadpour S, Shokraei S, Nasrollahzadeh Sabet M, Faridi-Majidi R, Ghanbari H. Development of electrically conductive hybrid nanofibers based on CNT-polyurethane nanocomposite for cardiac tissue engineering. Microsc Res Tech. 2019;82(8):1316-25. https://doi.org/10.1002/jemt.23282.
Hitscherich P, Aphale A, Gordan R, Whitaker R, Singh P, Xie LH, et al. Electroactive graphene composite scaffolds for cardiac tissue engineering. J Biomed Mater Res A. 2018;106(11):2923-33. https://doi.org/10.1002/jbm.a.36481.
Parker KK, Ingber DE. Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering. Philos Trans R Soc Lond B Biol Sci. 2007;362(1484):1267-79. https://doi.org/10.1098/rstb.2007.2114.
Sarker MD, Naghieh S, Sharma NK, Ning L, Chen X. Bioprinting of vascularized tissue scaffolds: influence of biopolymer, cells, growth factors, and gene delivery. J Healthc Eng. 2019;2019:9156921. https://doi.org/10.1155/2019/9156921.
Hall ML, Ogle BM. Cardiac extracellular matrix modification as a therapeutic approach. Adv Exp Med Biol. 2018;1098:131-50. https://doi.org/10.1007/978-3-319-97421-7_7.
Song R, Murphy M, Li C, Ting K, Soo C, Zheng Z. Current development of biodegradable polymeric materials for biomedical applications. Drug Des Devel Ther. 2018;12:3117-45. https://doi.org/10.2147/DDDT.S165440.
Liu F, Chen Q, Liu C, Ao Q, Tian X, Fan J, et al. Natural polymers for organ 3D bioprinting. Polymers (Basel). 2018;10(11):1278. https://doi.org/10.3390/polym10111278.
Chakraborty J, Roy S, Ghosh S. Regulation of decellularized matrix mediated immune response. Biomater Sci. 2020;8(5):1194-215. https://doi.org/10.1039/c9bm01780a.
Dzobo K, Motaung KSCM, Adesida A. Recent trends in decellularized extracellular matrix bioinks for 3D printing: an updated review. Int J Mol Sci. 2019;20(18):4628. https://doi.org/10.3390/ijms20184628.
Bejleri D, Davis ME. Decellularized extracellular matrix materials for cardiac repair and regeneration. Adv Healthc Mater. 2019;8(5):e1801217. https://doi.org/10.1002/adhm.201801217.
Moroni F, Mirabella T. Decellularized matrices for cardiovascular tissue engineering. Am J Stem Cells. 2014;3(1):1-20.
Huang S, Yang Y, Yang Q, Zhao Q, Ye X. Engineered circulatory scaffolds for building cardiac tissue. J Thorac Dis. 2018;10(Suppl 20):S2312-S2328. https://doi.org/10.21037/jtd.2017.12.92.
Efraim Y, Schoen B, Zahran S, Davidov T, Vasilyev G, Baruch L, et al. 3D Structure and processing methods direct the biological attributes of ECM-based cardiac scaffolds. Sci Rep. 2019;9(1):5578. https://doi.org/10.1038/s41598-019-41831-9.
Belviso I, Romano V, Sacco AM, Ricci G, Massai D, Cammarota M, et al. Decellularized human dermal matrix as a biological scaffold for cardiac repair and regeneration. Front Bioeng Biotechnol. 2020;8:229. https://doi.org/10.3389/fbioe.2020.00229.
Weinberger F, Mannhardt I, Eschenhagen T. Engineering cardiac muscle tissue: a maturating field of research. Circ Res. 2017;120(9):1487-500. https://doi.org/10.1161/CIRCRESAHA.117.310738.
Ott HC, Matthiesen TS, Goh SK, Black LD, Kren SM, Netoff TI, et al. Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart. Nat Med. 2008;14(2):213-21. https://doi.org/10.1038/nm1684.
Kc P, Hong Y, Zhang G. Cardiac tissue-derived extracellular matrix scaffolds for myocardial repair: advantages and challenges. Regen Biomater. 2019;6(4):185-99. https://doi.org/10.1093/rb/rbz017.
Sánchez PL, Fernández-Santos ME, Costanza S, Climent AM, Moscoso I, Gonzalez-Nicolas MA, et al. Acellular human heart matrix: a critical step toward whole heart grafts. Biomaterials. 2015;61:279-89. https://doi.org/10.1016/j.biomaterials.2015.04.056.
Taylor DA, Parikh RB, Sampaio LC. Bioengineering hearts: simple yet complex. Curr Stem Cell Rep. 2017;3(1):35-44. https://doi.org/10.1007/s40778-017-0075-7.
Müller P, Lemcke H, David R. Stem cell therapy in heart diseases - cell types, mechanisms and improvement strategies. Cell Physiol Biochem. 2018;48(6):2607-55. https://doi.org/10.1159/000492704.
Arai S, Lacerda C, Orton EC. Tissue-gel electrophoresis enhances antigen removal from porcine aortic valve and bovine pericardium. J Heart Valve Dis. 2010;19(6):753-8.
Song JJ, Ott HC. Organ engineering based on decellularized matrix scaffolds. Trends Mol Med. 2011;17(8):424-32. https://doi.org/10.1016/j.molmed.2011.03.005.
Boccafoschi F, Botta M, Fusaro L, Copes F, Ramella M, Cannas M. Decellularized biological matrices: an interesting approach for cardiovascular tissue repair and regeneration. J Tissue Eng Regen Med. 2017;11(5):1648-57. https://doi.org/10.1002/term.2103.
Gilpin A, Yang Y. Decellularization strategies for regenerative medicine: from processing techniques to applications. Biomed Res Int. 2017;2017:9831534. https://doi.org/10.1155/2017/9831534.
Wollmann L, Suss P, Mendonça J, Luzia C, Schittini A, Rosa GWXD, et al. Characterization of decellularized human pericardium for tissue engineering and regenerative medicine applications. Arq Bras Cardiol. 2019;113(1):11-7. https://doi.org/10.5935/abc.20190094.
Schmitt A, Csiki R, Tron A, Saldamli B, Tübel J, Florian K, et al. Optimized protocol for whole organ decellularization. Eur J Med Res. 2017;22(1):31. https://doi.org/10.1186/s40001-017-0272-y.
Sakina R, Llucià-Valldeperas A, Henriques Lourenço A, Harichandan A, Gelsomino S, Wieringa P, et al. Decellularization of porcine heart tissue to obtain extracellular matrix based hydrogels. Methods Cell Biol. 2020;157:3-21. https://doi.org/10.1016/bs.mcb.2019.11.023.
Bejleri D, Streeter BW, Nachlas ALY, Brown ME, Gaetani R, Christman KL, et al. A bioprinted cardiac patch composed of cardiac-specific extracellular matrix and progenitor cells for heart repair. Adv Healthc Mater. 2018;7(23):e1800672. https://doi.org/10.1002/adhm.201800672.
Kristen M, Ainsworth MJ, Chirico N, van der Ven CFT, Doevendans PA, Sluijter JPG, et al. Fiber scaffold patterning for mending hearts: 3D organization bringing the next step. Adv Healthc Mater. 2020;9(1):e1900775. https://doi.org/10.1002/adhm.201900775.
Capulli AK, MacQueen LA, Sheehy SP, Parker KK. Fibrous scaffolds for building hearts and heart parts. Adv Drug Deliv Rev. 2016;96:83-102. https://doi.org/10.1016/j.addr.2015.11.020.
Hasan A, Soliman S, El Hajj F, Tseng YT, Yalcin HC, Marei HE. Fabrication and in vitro characterization of a tissue engineered PCL-PLLA heart valve. Sci Rep. 2018;8(1):8187. https://doi.org/10.1038/s41598-018-26452-y.
Skylar-Scott MA, Uzel SGM, Nam LL, Ahrens JH, Truby RL, Damaraju S, et al. Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels. Sci Adv. 2019;5(9):eaaw2459. https://doi.org/10.1126/sciadv.aaw2459.
Ong CS, Nam L, Ong K, Krishnan A, Huang CY, Fukunishi T, et al. 3D and 4D bioprinting of the myocardium: current approaches, challenges, and future prospects. Biomed Res Int. 2018;2018:6497242. https://doi.org/10.1155/2018/6497242.
Heusch G. Myocardial ischemia: lack of coronary blood flow, myocardial oxygen supply-demand imbalance, or what? Am J Physiol Heart Circ Physiol. 2019;316(6):H1439-H1446. https://doi.org/10.1152/ajpheart.00139.2019.
Smit FE, Dohmen PM. Cardiovascular tissue engineering: where we come from and where are we now? Med Sci Monit Basic Res. 2015;21:1-3. https://doi.org/10.12659/MSMBR.893546.
Kikuchi K, Poss KD. Cardiac regenerative capacity and mechanisms. Annu Rev Cell Dev Biol. 2012;28:719-41. https://doi.org/10.1146/annurev-cellbio-101011-155739.
Orlando G, Soker S, Stratta RJ, Atala A. Will regenerative medicine replace transplantation? Cold Spring Harb Perspect Med. 2013;3(8):a015693. https://doi.org/10.1101/cshperspect.a015693.
Wang X. Bioartificial organ manufacturing technologies. Cell Transplant. 2019;28(1):5-17. https://doi.org/10.1177/0963689718809918.
Gaebel R, Ma N, Liu J, Guan J, Koch L, Klopsch C, et al. Patterning human stem cells and endothelial cells with laser printing for cardiac regeneration. Biomaterials. 2011;32(35):9218-30. https://doi.org/10.1016/j.biomaterials.2011.08.071.
Gaetani R, Doevendans PA, Metz CH, Alblas J, Messina E, Giacomello A, et al. Cardiac tissue engineering using tissue printing technology and human cardiac progenitor cells. Biomaterials. 2012;33(6):1782-90. https://doi.org/10.1016/j.biomaterials.2011.11.003.
Gaetani R, Feyen DA, Verhage V, Slaats R, Messina E, Christman KL, et al. Epicardial application of cardiac progenitor cells in a 3D-printed gelatin/hyaluronic acid patch preserves cardiac function after myocardial infarction. Biomaterials. 2015;61:339-48. https://doi.org/10.1016/j.biomaterials.2015.05.005.
Naskar D, Bhattacharjee P, Ghosh AK, Mandal M, Kundu SC. Carbon nanofiber reinforced nonmulberry silk protein fibroin nanobiocomposite for tissue engineering applications. ACS Appl Mater Interfaces. 2017;9(23):19356-70. https://doi.org/10.1021/acsami.6b04777.
Mehrotra S, Nandi SK, Mandal BB. Stacked silk-cell monolayers as a biomimetic three dimensional construct for cardiac tissue reconstruction. J Mater Chem B. 2017;5(31):6325-38. https://doi.org/10.1039/c7tb01494e.
Yeung E, Fukunishi T, Bai Y, Bedja D, Pitaktong I, Mattson G, et al. Cardiac regeneration using human-induced pluripotent stem cell-derived biomaterial-free 3D-bioprinted cardiac patch in vivo. J Tissue Eng Regen Med. 2019;13(11):2031-9. https://doi.org/10.1002/term.2954.
El-Hamamsy I, Bouhout I. The Ross procedure: time for a hard look at current practices and a reexamination of the guidelines. Ann Transl Med. 2017;5(6):142. https://doi.org/10.21037/atm.2017.01.64.
Moore M, Chen J, Mallow PJ, Rizzo JA. The direct health-care burden of valvular heart disease: evidence from US national survey data. Clinicoecon Outcomes Res. 2016;8:613-27. https://doi.org/10.2147/CEOR.S112691.
Turakhia MP, Shafrin J, Bognar K, Goldman DP, Mendys PM, Abdulsattar Y, et al. Economic burden of undiagnosed nonvalvular atrial fibrillation in the United States. Am J Cardiol. 2015;116(5):733-9. https://doi.org/10.1016/j.amjcard.2015.05.045.
van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, et al. Engineering a 3D-bioprinted model of human heart valve disease using nanoindentation-based biomechanics. Nanomaterials (Basel). 2018;8(5):296. https://doi.org/10.3390/nano8050296.
Duan B, Hockaday LA, Kang KH, Butcher JT. 3D bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels. J Biomed Mater Res A. 2013;101(5):1255-64. https://doi.org/10.1002/jbm.a.34420.
Lee A, Hudson AR, Shiwarski DJ, Tashman JW, Hinton TJ, Yerneni S, et al. 3D bioprinting of collagen to rebuild components of the human heart. Science. 2019;365(6452):482-7. https://doi.org/10.1126/science.aav9051.
Liu C, Qiao W, Cao H, Dai J, Li F, Shi J, et al. A riboflavin-ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility. Biomater Sci. 2020;8(9):2549-63. https://doi.org/10.1039/c9bm01956a.
Jia W, Gungor-Ozkerim PS, Zhang YS, Yue K, Zhu K, Liu W, et al. Direct 3D bioprinting of perfusable vascular constructs using a blend bioink. Biomaterials. 2016;106:58-68. https://doi.org/10.1016/j.biomaterials.2016.07.038.
Tomasina C, Bodet T, Mota C, Moroni L, Camarero-Espinosa S. Bioprinting vasculature: materials, cells and emergent techniques. Materials (Basel). 2019;12(17):2701. https://doi.org/10.3390/ma12172701.
Lee VK, Kim DY, Ngo H, Lee Y, Seo L, Yoo SS, et al. Creating perfused functional vascular channels using 3D bio-printing technology. Biomaterials. 2014;35(28):8092-102. https://doi.org/10.1016/j.biomaterials.2014.05.083.
Arai K, Murata D, Verissimo AR, Mukae Y, Itoh M, Nakamura A, et al. Fabrication of scaffold-free tubular cardiac constructs using a Bio-3D printer. PLoS One. 2018;13(12):e0209162. https://doi.org/10.1371/journal.pone.0209162.
Liu H, Kitano S, Irie S, Levato R, Matsusaki M. Collagen microfibers induce blood capillary orientation and open vascular lumen. Adv Biosyst. 2020;4(5):e2000038. https://doi.org/10.1002/adbi.202000038.
Roche CD, Brereton RJL, Ashton AW, Jackson C, Gentile C. Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery. Eur J Cardiothorac Surg. 2020;58(3):500-10. https://doi.org/10.1093/ejcts/ezaa093.
Vijayavenkataraman S, Vialli N, Fuh JYH, Lu WF. Conductive collagen/polypyrrole-b-polycaprolactone hydrogel for bioprinting of neural tissue constructs. Int J Bioprint. 2019;5(2.1):229. https://doi.org/10.18063/ijb.v5i2.1.229.
Ozbolat IT, Yu Y. Bioprinting toward organ fabrication: challenges and future trends. IEEE Trans Biomed Eng. 2013;60(3):691-9. https://doi.org/10.1109/TBME.2013.2243912.