Dietary l-carnitine Supplementation Modifies the Lipopolysaccharide-Induced Acute Phase Reaction in Dairy Cows.

clinical score dairy cow energy metabolism insulin l-carnitine lipopolysaccharide non-esterified fatty acids performance systemic inflammation

Journal

Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614

Informations de publication

Date de publication:
10 Jan 2021
Historique:
received: 22 12 2020
accepted: 08 01 2021
entrez: 13 1 2021
pubmed: 14 1 2021
medline: 14 1 2021
Statut: epublish

Résumé

l-carnitine plays an important role in energy metabolism through supporting the transport of activated fatty acids to the subcellular site of β-oxidation. An acute phase reaction (APR) is known as an energy consuming process. Lipopolysaccharides (LPS) are often used in animal models to study intervention measures during innate immune responses such as APR. Thus, the aim of the study was to investigate the effects of dietary l-carnitine supplementation during an LPS-induced APR in mid-lactating German Holstein cows. Animals were assigned to a control (CON, n = 26) or l-carnitine group (CAR,

Identifiants

pubmed: 33435209
pii: ani11010136
doi: 10.3390/ani11010136
pmc: PMC7828073
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : 202989534

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Auteurs

Jennifer Meyer (J)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Susanne Ursula Kononov (SU)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.
Institute of Animal Science, Functional Anatomy of Livestock, University of Hohenheim, Fruwirthstraße 35, 70593 Stuttgart, Germany.

Sandra Grindler (S)

Institute of Animal Science, Functional Anatomy of Livestock, University of Hohenheim, Fruwirthstraße 35, 70593 Stuttgart, Germany.

Johanna Tröscher-Mußotter (J)

Institute of Animal Science, Functional Microbiology of Livestock, University of Hohenheim, Emil-Wolff-Str. 8, 70593 Stuttgart, Germany.

Mohamad Taher Alaedin (MT)

Institute for Animal Science, Physiology and Hygiene, Rheinische Friedrich-Wilhelms-Universität Bonn, Katzenburgweg 7-9, 53115 Bonn, Germany.

Jana Frahm (J)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Liane Hüther (L)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Jeannette Kluess (J)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Susanne Kersten (S)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Dirk von Soosten (D)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Ulrich Meyer (U)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Erika Most (E)

Institute of Animal Nutrition and Nutrition Physiology, Justus-Liebig-Universität Gießen, Heinrich-Buff-Ring 26-32, 35392 Gießen, Germany.

Klaus Eder (K)

Institute of Animal Nutrition and Nutrition Physiology, Justus-Liebig-Universität Gießen, Heinrich-Buff-Ring 26-32, 35392 Gießen, Germany.

Helga Sauerwein (H)

Institute for Animal Science, Physiology and Hygiene, Rheinische Friedrich-Wilhelms-Universität Bonn, Katzenburgweg 7-9, 53115 Bonn, Germany.

Jana Seifert (J)

Institute of Animal Science, Functional Microbiology of Livestock, University of Hohenheim, Emil-Wolff-Str. 8, 70593 Stuttgart, Germany.

Korinna Huber (K)

Institute of Animal Science, Functional Anatomy of Livestock, University of Hohenheim, Fruwirthstraße 35, 70593 Stuttgart, Germany.

Anja Wegerich (A)

Clinic for Cattle, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173 Hannover, Germany.

Jürgen Rehage (J)

Clinic for Cattle, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173 Hannover, Germany.

Sven Dänicke (S)

Institute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.

Classifications MeSH