[A Case of Extragonadal Germ Cell Tumor Treated by Induction Therapy with A Reduced Bep Regimen].


Journal

Hinyokika kiyo. Acta urologica Japonica
ISSN: 0018-1994
Titre abrégé: Hinyokika Kiyo
Pays: Japan
ID NLM: 0421145

Informations de publication

Date de publication:
Dec 2020
Historique:
entrez: 13 1 2021
pubmed: 14 1 2021
medline: 15 1 2021
Statut: ppublish

Résumé

A 21-year-old man with chief complaints of left hypochondriac and chest pain was shown to have multiple masses in the lung, a pleural effusion in the right cavum thoracis, a mediastinal mass, and lymphadenopathy detected by computed tomographic scan. He was diagnosed with an extragonadal germ cell tumor based on pathologic findings from lung biopsies and elevation of the serum total human chorionic gonadotropin. He underwent a reduced chemotherapy regimen consisting of bleomycin, cisplatin, and etoposide (reduced BEP) to lower the risk of acute respiratory distress syndrome (ARDS), a manifestation of choriocarcinoma syndrome, which occurs at induction chemotherapy with the full-dose BEP regimen. Choriocarcinoma syndrome did not develop during chemotherapy, and he has been disease-free since salvage chemotherapy and subsequent retroperitoneal lymph node dissection.

Identifiants

pubmed: 33435656
doi: 10.14989/ActaUrolJap_66_12_449
doi:

Substances chimiques

Bleomycin 11056-06-7
Etoposide 6PLQ3CP4P3
Cisplatin Q20Q21Q62J

Types de publication

Case Reports Journal Article

Langues

jpn

Sous-ensembles de citation

IM

Pagination

449-452

Auteurs

Shunsuke Owa (S)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Takeshi Sasaki (T)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Mikiya Ishihara (M)

The Department of Medical Oncology, Mie University Graduate School of Medicine.

Susumu Watanabe (S)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Momoko Kato (M)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Yusuke Sugino (Y)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Manabu Kato (M)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Satoru Masui (S)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Kouhei Nishikawa (K)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Yuko Yoshio (Y)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Hideki Kanda (H)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

Yoshiki Sugimura (Y)

The Urology and Prostate Center, Murase Hospital.

Takahiro Inoue (T)

The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine.

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