[A Case of Extragonadal Germ Cell Tumor Treated by Induction Therapy with A Reduced Bep Regimen].
Journal
Hinyokika kiyo. Acta urologica Japonica
ISSN: 0018-1994
Titre abrégé: Hinyokika Kiyo
Pays: Japan
ID NLM: 0421145
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
entrez:
13
1
2021
pubmed:
14
1
2021
medline:
15
1
2021
Statut:
ppublish
Résumé
A 21-year-old man with chief complaints of left hypochondriac and chest pain was shown to have multiple masses in the lung, a pleural effusion in the right cavum thoracis, a mediastinal mass, and lymphadenopathy detected by computed tomographic scan. He was diagnosed with an extragonadal germ cell tumor based on pathologic findings from lung biopsies and elevation of the serum total human chorionic gonadotropin. He underwent a reduced chemotherapy regimen consisting of bleomycin, cisplatin, and etoposide (reduced BEP) to lower the risk of acute respiratory distress syndrome (ARDS), a manifestation of choriocarcinoma syndrome, which occurs at induction chemotherapy with the full-dose BEP regimen. Choriocarcinoma syndrome did not develop during chemotherapy, and he has been disease-free since salvage chemotherapy and subsequent retroperitoneal lymph node dissection.
Identifiants
pubmed: 33435656
doi: 10.14989/ActaUrolJap_66_12_449
doi:
Substances chimiques
Bleomycin
11056-06-7
Etoposide
6PLQ3CP4P3
Cisplatin
Q20Q21Q62J
Types de publication
Case Reports
Journal Article
Langues
jpn
Sous-ensembles de citation
IM