Korean Red Ginseng aqueous extract improves markers of mucociliary clearance by stimulating chloride secretion.

CFTR Chloride channels Mucociliary clearance Red Ginseng Sinusitis

Journal

Journal of ginseng research
ISSN: 1226-8453
Titre abrégé: J Ginseng Res
Pays: Korea (South)
ID NLM: 100890690

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 16 08 2018
revised: 30 08 2019
accepted: 06 09 2019
entrez: 13 1 2021
pubmed: 14 1 2021
medline: 14 1 2021
Statut: ppublish

Résumé

Abnormal chloride (Cl Primary murine nasal septal epithelial (MNSE) [wild-type (WT) and transgenic CFTR RGAE (at 30μg/mL of ginsenosides) significantly increased Cl RGAE augments ASL depth and CBF by stimulating Cl

Sections du résumé

BACKGROUND BACKGROUND
Abnormal chloride (Cl
METHODS METHODS
Primary murine nasal septal epithelial (MNSE) [wild-type (WT) and transgenic CFTR
RESULTS RESULTS
RGAE (at 30μg/mL of ginsenosides) significantly increased Cl
CONCLUSION CONCLUSIONS
RGAE augments ASL depth and CBF by stimulating Cl

Identifiants

pubmed: 33437158
doi: 10.1016/j.jgr.2019.09.001
pii: S1226-8453(18)30275-6
pmc: PMC7790903
doi:

Types de publication

Journal Article

Langues

eng

Pagination

66-74

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK072482
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL133006
Pays : United States
Organisme : NHLBI NIH HHS
ID : R35 HL135816
Pays : United States
Organisme : NIEHS NIH HHS
ID : U01 ES026458
Pays : United States

Informations de copyright

© 2019 The Korean Society of Ginseng, Published by Elsevier Korea LLC.

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Auteurs

Do-Yeon Cho (DY)

Department of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Daniel Skinner (D)

Department of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Shaoyan Zhang (S)

Department of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Ahmed Lazrak (A)

Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Dong Jin Lim (DJ)

Department of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Christopher G Weeks (CG)

Department of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Catherine G Banks (CG)

Department of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Chang Kyun Han (CK)

Korea Ginseng Research Institute, Korea Ginseng Corporation, Daejeon, Republic of Korea.

Si-Kwan Kim (SK)

Department of Biomedical Chemistry, Konkuk University, Chungju, Republic of Korea.

Guillermo J Tearney (GJ)

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States.

Sadis Matalon (S)

Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Steven M Rowe (SM)

Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Departments of Medicine, Pediatrics, Cell Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Bradford A Woodworth (BA)

Department of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Classifications MeSH