A novel G26A variation in 5' half of TGIF1 gene associates with high myopia in ethnic Kashmiri population from India.
Ethnic
TG1F1
gene
myopia
novel
variation
Journal
Taiwan journal of ophthalmology
ISSN: 2211-5072
Titre abrégé: Taiwan J Ophthalmol
Pays: India
ID NLM: 101582127
Informations de publication
Date de publication:
Historique:
received:
20
02
2019
accepted:
15
06
2019
entrez:
13
1
2021
pubmed:
17
10
2019
medline:
17
10
2019
Statut:
epublish
Résumé
This study aims to look at novel variations in TGIF1 gene and explores their potential association with high myopia in an ethnic population from Kashmir (India). Genomic DNA was genotyped for polymorphic variations, and allele frequencies were tested for the Hardy-Weinberg disequilibrium in 240 ethnic Kashmiri cases with high myopia with a spherical equivalent of >-6 diopters (D) and compared with emmetropic controls with spherical equivalent within -0.5D in one or both eyes represented by a sample size of 228. In this study, we found a novel sequence variation G26A (GAT to AAT) in 5' half of TGIF1 gene (p. aspartic acid >asparagine) at a frequency of 62% (148/240,
Identifiants
pubmed: 33437604
doi: 10.4103/tjo.tjo_16_19
pii: TJO-10-294
pmc: PMC7787093
doi:
Types de publication
Journal Article
Langues
eng
Pagination
294-297Informations de copyright
Copyright: © 2019 Taiwan J Ophthalmol.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interests of this paper.
Références
Prog Retin Eye Res. 2010 Nov;29(6):520-42
pubmed: 20576483
Invest Ophthalmol Vis Sci. 2006 May;47(5):1794-802
pubmed: 16638983
Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10325-9
pubmed: 8234293
Nat Commun. 2018 May 3;9(1):1782
pubmed: 29725004
Eye Contact Lens. 2018 Jul;44(4):231-247
pubmed: 29901472
Invest Ophthalmol Vis Sci. 1996 Nov;37(12):2519-26
pubmed: 8933768
J Mol Biol. 1990 Jun 20;213(4):859-83
pubmed: 2359125
Prog Retin Eye Res. 2012 Nov;31(6):622-60
pubmed: 22772022
Optom Vis Sci. 2015 Jul;92(7):741-9
pubmed: 26002010
Proteins. 2000 Aug 15;40(3):525-37
pubmed: 10861944
Clin Genet. 2011 Apr;79(4):301-20
pubmed: 21155761
Clin Exp Optom. 2003 Sep;86(5):276-88
pubmed: 14558849
Nucleic Acids Res. 1997 Dec 15;25(24):4876-82
pubmed: 9396791
Curr Eye Res. 2014 Mar;39(3):282-90
pubmed: 24215395
Optom Vis Sci. 2009 Jan;86(1):E8-E22
pubmed: 19104467
Proteins. 2007;69 Suppl 8:108-17
pubmed: 17894355
Mol Vis. 2005 Feb 02;11:97-110
pubmed: 15723005
PLoS Genet. 2015 Aug 27;11(8):e1005432
pubmed: 26313004
Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1012-5
pubmed: 12601022
BMC Med Genet. 2004 Aug 03;5:20
pubmed: 15291966
Mol Vis. 2006 Jun 21;12:698-703
pubmed: 16807529
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Oct;20(5):454-6
pubmed: 14556208
Ophthalmic Physiol Opt. 1997 Jul;17(4):279-90
pubmed: 9390372
Arch Ophthalmol. 1999 May;117(5):658-63
pubmed: 10326965
Immunogenetics. 2006 Dec;58(12):947-53
pubmed: 17048038
Am J Hum Genet. 1998 Jul;63(1):109-19
pubmed: 9634508