Implementation of the microdosimetric kinetic model using analytical microdosimetry in a treatment planning system for proton therapy.

Humans Kinetics Proton Therapy Protons Relative Biological Effectiveness
MKM Microdosimetry Particle therapy Proton therapy RBE yD calculation

Journal

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
ISSN: 1724-191X
Titre abrégé: Phys Med
Pays: Italy
ID NLM: 9302888

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 10 08 2020
revised: 17 10 2020
accepted: 19 11 2020
pubmed: 14 1 2021
medline: 25 6 2021
entrez: 13 1 2021
Statut: ppublish

Résumé

To implement RBE calculations in treatment planning systems based on the Microdosimetric Kinetic Model (MKM) upon analytical calculations of dose-mean lineal energy (y The radius of a domain (r Differences between model-based predictions and experimentally determined RBE are analyzed for y Microdosimetry calculations at the TPS-level provide tools to improve predictions of RBE using the MKM with actual values of y

Identifiants

DOI: 10.1016/j.ejmp.2020.11.024 PMID: 33440283
pubmed: 33440283
pii: S1120-1797(20)30298-2
doi: 10.1016/j.ejmp.2020.11.024
pii:
doi:

Substances chimiques

Protons 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

69-76

Informations de copyright

Copyright © 2020. Published by Elsevier Ltd.

Auteurs

A Bertolet (A)

Department of Radiation Oncology, Hospital of The University of Pennsylvania, Philadelphia, PA, USA; Department of Atomic, Molecular and Nuclear Physics, Universidad de Sevilla, Seville, Spain.

M A Cortés-Giraldo (MA)

Department of Atomic, Molecular and Nuclear Physics, Universidad de Sevilla, Seville, Spain.

A Carabe-Fernandez (A)

Department of Radiation Oncology, Hospital of The University of Pennsylvania, Philadelphia, PA, USA. Electronic address: a.carabe@hamptonproton.org.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Implementation of the microdosimetric kinetic...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Implementation of the microdosimetric kinetic...
questionsmedicales.fr › Thérapeutique › Radiothérapie › Radiothérapie par ions lourds › Protonthérapie › Implementation of the microdosimetric kinetic...
questionsmedicales.fr › Phénomènes physiques › Particules élémentaires › Nucléons › Protons › Implementation of the microdosimetric kinetic...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Hygiène radiologique › Dose de rayonnement › Efficacité biologique relative › Implementation of the microdosimetric kinetic...