A Systematic Review on the Association between Lipid Accumulation Product Index and Type 2 Diabetes Mellitus.
insulin resistance
lipid accumulation product
obesity
type 2 diabetes mellitus
Journal
Journal of the ASEAN Federation of Endocrine Societies
ISSN: 0857-1074
Titre abrégé: J ASEAN Fed Endocr Soc
Pays: Philippines
ID NLM: 8608483
Informations de publication
Date de publication:
2019
2019
Historique:
received:
20
01
2019
accepted:
02
04
2019
entrez:
14
1
2021
pubmed:
1
1
2019
medline:
1
1
2019
Statut:
ppublish
Résumé
Excess fat accumulation contributes to the development of type 2 diabetes mellitus (T2DM). Lipid accumulation product (LAP) is an index computed from waist circumference and triglycerides, which represents increased lipotoxicity. We aim to study the relationship of LAP index and T2DM and its utility as a predictor for T2DM development. A literature search in PubMed and Cochrane database was performed to retrieve and review studies reporting the association between LAP and T2DM. Two cross-sectional studies from Japan and the United States, and one cohort study from Iran were obtained. A high LAP was associated with a higher risk of T2DM [odds ratio (OR) 19.1, 95% confidence interval (CI) (6.6-55.5) for women; and OR 7.4, 95% CI (5.1-10.8) for men]. LAP was strongly associated with T2DM. Its utility in predicting the development of T2DM needs to be confirmed.
Identifiants
pubmed: 33442132
doi: 10.15605/jafes.034.01.04
pii: JAFES-34-1-016
pmc: PMC7784243
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
16-20Informations de copyright
© 2019 Journal of the ASEAN Federation of Endocrine Societies.
Déclaration de conflit d'intérêts
The authors declared no conflict of interest.
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