What Is a Cytokine Storm and Should It Matter to Me?
Journal
The Journal of the American Academy of Orthopaedic Surgeons
ISSN: 1940-5480
Titre abrégé: J Am Acad Orthop Surg
Pays: United States
ID NLM: 9417468
Informations de publication
Date de publication:
01 04 2021
01 04 2021
Historique:
received:
08
10
2020
accepted:
09
12
2020
pubmed:
15
1
2021
medline:
30
3
2021
entrez:
14
1
2021
Statut:
ppublish
Résumé
The recent COVID-19 pandemic has brought attention to cytokines and the phenomenon of cytokine storm into mainstream discussions. In this disease specifically, a cytokine storm overwhelming immune response contributes to the pathophysiology and mortality of the COVID-19 infection. Analogous perturbed immune reactions are experienced in polytrauma patients, compromising local tissue healing while threatening multiple organ systems. The expanding field of osteoimmunology should contribute to the orthopaedic community's understanding of how the immune system response, whether normal or pathologic, affects the whole body outcome of our patients.
Identifiants
pubmed: 33443384
doi: 10.5435/JAAOS-D-20-00805
pii: 00124635-202104010-00006
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
297-299Informations de copyright
Copyright © 2021 by the American Academy of Orthopaedic Surgeons.
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