Is Adjunctive Hyperbaric Oxygen Treatment Alone or with Surgery the Proper Management for Active and Persistent Osteoradionecrosis?


Journal

Advances in skin & wound care
ISSN: 1538-8654
Titre abrégé: Adv Skin Wound Care
Pays: United States
ID NLM: 100911021

Informations de publication

Date de publication:
01 Feb 2021
Historique:
entrez: 14 1 2021
pubmed: 15 1 2021
medline: 21 10 2021
Statut: ppublish

Résumé

This study enrolled patients with stage 3 osteoradionecrosis. There were three treatment modalities: antibiotics, hyperbaric oxygen therapy (HBOT), and surgery. Complete healing was the primary outcome. Multiple logistic regression analysis demonstrated that surgery with HBOT improved wound healing better than HBOT alone.

Identifiants

pubmed: 33443917
doi: 10.1097/01.ASW.0000725164.18431.a7
pii: 00129334-202102000-00012
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Pagination

1-4

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Références

Epstein JB, Wong FL, Dickens A, et al. Bone and gallium scans in postradiotherapy osteonecrosis of the jaw. Head Neck 1992;14(4):288–92.
Chronopoulos A, Zarra T, Ehrenfeld M, Otto S. Osteoradionecrosis of the jaws: definition, epidemiology, staging and clinical and radiological findings. A concise review. Int Dent J 2018;68(1):22–30.
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Schortinghuis J, Stegenga B, Raghoebar GM, de Bont LGM. Ultrasound stimulation of maxillofacial bone healing. Crit Rev Oral Biol Med 2003;14(1):63–74.
Fan H, Kim SM, Cho YJ, et al. New approach for the treatment of osteoradionecrosis with pentoxifylline and tocopherol. Biomater Res 2014;18:13.
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Auteurs

Kamonwan Jenwitheesuk (K)

At Khon Kaen University, Khon Kaen, Thailand, Kamonwan Jenwitheesuk, MD, is Associate Professor, Plastic & Reconstructive Unit, Department of Surgery, Faculty of Medicine; Ajanee Mahakkanukrauh, MD, is Associate Professor, Division of Allergy-Immunology-Rheumatology, Faculty of Medicine; Wiyada Punjaruk, MD, PhD, is Assistant Professor, Department of Physiology, Faculty of Medicine; Patravoot Vatanasapt, MD, is Assistant Professor, Head & Neck Surgery Unit, Department of Otorhinolaryngology, Faculty of Medicine; Kriangsak Jenwitheesuk, MD, is Associate Professor, General Surgery Unit, Department of Surgery, Faculty of Medicine; Palakorn Surakunprapha, MD, is Assistant Professor, Plastic & Reconstructive Unit, Department of Surgery, Faculty of Medicine; Suthin Jinaporntham, MD, DDS, is Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry; Krittinant Uraiwan, DDS, is Maxillofacial Surgeon, Dental Department, Srinagarind Hospital, Faculty of Medicine; and Phasuk Limrattanapimpa, MNS, is Nurse Specialist, Hyperbaric Oxygen Therapy Unit, Srinagarind Hospital, Faculty of Medicine. Acknowledgments: The authors thank University of Wisconsin Professor Emeritus James A. Will for assistance with the English language presentation of the manuscript under the aegis of the Publication Clinic, Research Affairs, Faculty of Medicine, KKU. This study was funded by a grant from Khon Kaen University, Faculty of Medicine (no. MN61203). The authors have disclosed no other financial relationships related to this article. Submitted January 15, 2020; accepted in revised form March 4, 2020.

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