Elevated Expression of
5-HTT
GTS
Gilles de la Tourette syndrome
OCD
SERT
SLC6A4
expression
methylation
obsessive compulsive disorder
serotonin
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
12 01 2021
12 01 2021
Historique:
received:
21
12
2020
revised:
08
01
2021
accepted:
09
01
2021
entrez:
15
1
2021
pubmed:
16
1
2021
medline:
22
7
2021
Statut:
epublish
Résumé
Gilles de la Tourette syndrome (GTS) is a complex neurodevelopmental disorder characterized by motor and vocal tics. Most of the GTS individuals have comorbid diagnoses, of which obsessive-compulsive disorder (OCD) and attention deficit-hyperactivity disorder (ADHD) are the most common. Several neurotransmitter systems have been implicated in disease pathogenesis, and amongst these, the dopaminergic and the serotonergic pathways are the most widely studied. In this study, we aimed to investigate whether the serotonin transporter (SERT) gene (
Identifiants
pubmed: 33445578
pii: genes12010086
doi: 10.3390/genes12010086
pmc: PMC7827645
pii:
doi:
Substances chimiques
SLC6A4 protein, human
0
Serotonin Plasma Membrane Transport Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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