Body weight variability is not associated with changes in risk factors for cardiometabolic disease.

Cardiometabolic disease Weight cycling Weight variability

Journal

International Journal of Cardiology. Hypertension
ISSN: 2590-0862
Titre abrégé: Int J Cardiol Hypertens
Pays: Netherlands
ID NLM: 101773659

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 02 06 2020
revised: 14 07 2020
accepted: 17 07 2020
entrez: 15 1 2021
pubmed: 16 1 2021
medline: 16 1 2021
Statut: epublish

Résumé

Weight loss is known to improve health, however the influence of variability in body weight around the overall trajectory on these outcomes is unknown. Few studies have measured body weight frequently enough to accurately estimate the variability component. To investigate the association of 12-month weight variability and concurrent weight change with changes in health markers and body composition. This study was a secondary analysis of the NoHoW trial, a 2 × 2 factorial randomised controlled trial promoting evidence-based behaviour change for weight loss maintenance. Outcome measurements related to cardiometabolic health and body composition were taken at 0, 6 and 12 months. Participants were provided with Wi-Fi connected smart scales (Fitbit Aria 2) and asked to self-weigh regularly over this period. Associations of weight variability and weight change with change in outcomes were investigated using multiple linear regression with multiple levels of adjustment in 955 participants. Twelve models were generated for each health marker. Associations between weight variability and changes in health markers were inconsistent between models and showed no evidence of a consistent relationship, with all effects explaining <1% of the outcome, and most 0%. Weight loss was consistently associated with improvements in health and body composition, with the greatest effects seen in percent body fat (R Over 12-months, weight variability was not consistently associated with any measure of cardiometabolic health or body composition, however weight loss consistently improved all outcomes. ISRCTN88405328.

Identifiants

pubmed: 33447771
doi: 10.1016/j.ijchy.2020.100045
pii: S2590-0862(20)30022-7
pmc: PMC7803052
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100045

Informations de copyright

© 2020 The Authors.

Déclaration de conflit d'intérêts

All named authors have nothing to declare.

Références

Int J Obes Relat Metab Disord. 2000 Sep;24(9):1226-30
pubmed: 11033995
J Am Heart Assoc. 2019 Apr 2;8(7):e010793
pubmed: 31025893
Obes Rev. 2015 Feb;16 Suppl 1:7-18
pubmed: 25614199
J Clin Endocrinol Metab. 2019 Mar 1;104(3):639-646
pubmed: 30500906
Physiol Behav. 2018 Oct 1;194:184-190
pubmed: 29842854
Am J Med Sci. 2005 Jun;329(6):276-91
pubmed: 15958870
BMJ. 2001 Nov 10;323(7321):1123-4
pubmed: 11701584
J Am Diet Assoc. 2009 Apr;109(4):718-24
pubmed: 19328269
BMJ Open. 2019 Sep 30;9(9):e029425
pubmed: 31575569
Lancet Public Health. 2017 May 19;2(6):e277-e285
pubmed: 28626830
Am J Epidemiol. 1995 Dec 15;142(12):1306-14
pubmed: 7503051
BMJ. 2017 Nov 14;359:j4849
pubmed: 29138133
Biores Open Access. 2018 Jun 01;7(1):90-100
pubmed: 29892497
Int J Obes (Lond). 2017 Mar;41(3):402-411
pubmed: 27840414
Diabetes Res Clin Pract. 2018 May;139:230-238
pubmed: 29574105
Diabetes Care. 2006 Sep;29(9):2102-7
pubmed: 16936160
Obes Res. 1999 Mar;7(2):170-8
pubmed: 10102254
Diabetes Metab Res Rev. 2008 Nov-Dec;24(8):624-8
pubmed: 18802932
Exp Ther Med. 2018 Sep;16(3):2052-2059
pubmed: 30186439
J Obes. 2014;2014:614519
pubmed: 25197563
JMIR Mhealth Uhealth. 2018 Aug 09;6(8):e10527
pubmed: 30093371
Physiol Meas. 2006 Sep;27(9):921-33
pubmed: 16868355
PLoS One. 2012;7(7):e39837
pubmed: 22848362
BMJ Open. 2017 Jun 8;7(5):e014684
pubmed: 28596244
JAMA Netw Open. 2019 Mar 1;2(3):e190731
pubmed: 30874785
N Engl J Med. 2017 Apr 6;376(14):1332-1340
pubmed: 28379800
Int J Cardiol. 2014 Mar 15;172(2):e263-4
pubmed: 24508493
Pathology. 2019 Feb;51(2):222-226
pubmed: 30528924
Front Endocrinol (Lausanne). 2019 Nov 08;10:728
pubmed: 31787929
Am J Cardiol. 2019 Feb 15;123(4):576-581
pubmed: 30553512
J Diabetes Investig. 2017 Jul;8(4):501-509
pubmed: 28083921
Int J Obes Relat Metab Disord. 2001 Jul;25(7):1063-7
pubmed: 11443507
Int J Obes Relat Metab Disord. 1996 Aug;20(8):704-9
pubmed: 8856391
JMIR Mhealth Uhealth. 2020 Sep 11;8(9):e17977
pubmed: 32915155
J Clin Med. 2019 Jun 30;8(7):
pubmed: 31261984
J Am Coll Cardiol. 2000 Nov 1;36(5):1565-71
pubmed: 11079659
Int J Behav Nutr Phys Act. 2011 Jul 28;8:79
pubmed: 21798015
Am J Epidemiol. 1995 Mar 1;141(5):461-5
pubmed: 7879790
Diabetes Care. 2011 Jul;34(7):1481-6
pubmed: 21593294
Circulation. 2018 Dec 4;138(23):2627-2637
pubmed: 30571256
Int J Obes. 1990 Apr;14(4):303-10
pubmed: 2361807
Sci Rep. 2019 Jul 2;9(1):9543
pubmed: 31266987
PLoS One. 2017 Apr 3;12(4):e0175057
pubmed: 28369119
BMJ Open. 2016 Jul 26;6(7):e010836
pubmed: 27466237
Br J Sports Med. 2020 Mar;54(6):332-340
pubmed: 30194221
J Hum Hypertens. 2005 Jan;19(1):61-7
pubmed: 15343355
Eur J Med Res. 2017 Oct 25;22(1):43
pubmed: 29070064
Int J Obes (Lond). 2019 Feb;43(2):412-423
pubmed: 29777238

Auteurs

Jake Turicchi (J)

Appetite Control and Energy Balance Group, School of Psychology, University of Leeds, Leeds, UK.

Ruairi O'Driscoll (R)

Appetite Control and Energy Balance Group, School of Psychology, University of Leeds, Leeds, UK.

Graham Horgan (G)

Biomathematics & Statistics Scotland, Aberdeen, UK.

Cristiana Duarte (C)

Appetite Control and Energy Balance Group, School of Psychology, University of Leeds, Leeds, UK.

Inês Santos (I)

Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal.

Jorge Encantado (J)

Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal.

Antonio L Palmeira (AL)

Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal.

Sofus C Larsen (SC)

Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.

Jack K Olsen (JK)

Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.

Berit L Heitmann (BL)

Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.
The Boden Institute of Obesity, Nutrition and Eating Disorder, University of Sydney, Sydney, Australia.
Department of Public Health, Section for General Medicine, University of Copenhagen, Copenhagen, Denmark.

R James Stubbs (RJ)

Appetite Control and Energy Balance Group, School of Psychology, University of Leeds, Leeds, UK.

Classifications MeSH