Total knee arthroplasty improves the quality-adjusted life years in patients who exceeded their estimated life expectancy.


Journal

International orthopaedics
ISSN: 1432-5195
Titre abrégé: Int Orthop
Pays: Germany
ID NLM: 7705431

Informations de publication

Date de publication:
03 2021
Historique:
received: 03 10 2020
accepted: 17 12 2020
pubmed: 16 1 2021
medline: 24 4 2021
entrez: 15 1 2021
Statut: ppublish

Résumé

Total knee arthroplasty (TKA) is the treatment of choice for end-stage osteoarthritis though its risk-benefit ratio in elderly patients remains debated. This study aimed to evaluate the functional outcome, rates of complication and mortality, and quality-adjusted life years (QALY) in patients who exceeded their estimated life expectancy. Ninety-seven TKA implanted in 86 patients who exceeded their estimated life expectancy at the time of TKA were prospectively included in our institutional joint registry and retrospectively analyzed. At latest follow-up, the functional outcome with the Knee Society Score (KSS), rates of complication and mortality, and QALY with utility value of EuroQol-5D score were evaluated. At a mean follow-up of three ± one years, the pre- to post-operative KSS improved significantly (p < 0.01). The rates of surgical and major medical complications related to TKA were 3% and 10%, respectively. The re-operation rate with readmission was 3% while no TKA was revised. The 30-day and one year mortality was 1% and 3%, respectively. The pre- to one year post-operative QALY improved significantly (p < 0.01). The cumulative QALY five years after TKA was four years. Assuming that these patients did not undergo TKA, their cumulative QALY at five years would have been only two years. TKA is an effective procedure for the treatment of end-stage osteoarthritis in patients who exceeded their estimated life expectancy. TKA provided significant improvement in function and quality of life without adversely affecting overall morbidity and mortality. Therefore, TKA should not be contra-indicated in elderly patients based on their advanced age alone.

Identifiants

pubmed: 33447874
doi: 10.1007/s00264-020-04917-y
pii: 10.1007/s00264-020-04917-y
pmc: PMC7892693
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

635-641

Commentaires et corrections

Type : CommentIn

Références

J Arthroplasty. 2007 Sep;22(6):807-11
pubmed: 17826269
J Arthroplasty. 2015 Dec;30(12):2102-5.e1
pubmed: 26169454
Am J Public Health. 1994 Mar;84(3):351-8
pubmed: 8129049
J Bone Joint Surg Am. 2018 Sep 5;100(17):1455-1460
pubmed: 30180053
Br Med Bull. 2010;96:5-21
pubmed: 21037243
J Arthroplasty. 2016 Sep;31(9 Suppl):59-62
pubmed: 27262420
J Arthroplasty. 2018 Nov;33(11):3484-3489
pubmed: 30054212
J Arthroplasty. 2014 Aug;29(8):1635-8
pubmed: 24767951
JB JS Open Access. 2018 Aug 15;3(3):e0007
pubmed: 30533590
Knee Surg Sports Traumatol Arthrosc. 2020 May;28(5):1473-1478
pubmed: 31111184
Anaesthesia. 2017 Feb;72(2):233-247
pubmed: 27996086
J Arthroplasty. 2012 Oct;27(9):1599-603
pubmed: 22552218
BMC Musculoskelet Disord. 2020 Jan 31;21(1):62
pubmed: 32005208
Clin Orthop Relat Res. 2014 Jan;472(1):181-7
pubmed: 23645339
J Arthroplasty. 2006 Sep;21(6 Suppl 2):151-6
pubmed: 16950078
J Bone Joint Surg Am. 2005 Mar;87(3):570-6
pubmed: 15741624
Arch Phys Med Rehabil. 2016 May;97(5):691-700
pubmed: 26792619
Bone Joint J. 2015 Nov;97-B(11):1512-8
pubmed: 26530654
Acta Orthop Belg. 2012 Dec;78(6):745-50
pubmed: 23409570
Health Policy Plan. 2006 Sep;21(5):402-8
pubmed: 16877455
Clin Orthop Relat Res. 2004 Jan;(418):179-83
pubmed: 15043112
Clin Orthop Relat Res. 2011 May;469(5):1391-400
pubmed: 21347818
J Arthroplasty. 2003 Oct;18(7):817-21
pubmed: 14566733
J Arthroplasty. 2018 Aug;33(8):2423-2427
pubmed: 29681494
J Bone Joint Surg Am. 2018 Jun 20;100(12):1064-1070
pubmed: 29916935
Bone Joint J. 2013 Jan;95-B(1):115-21
pubmed: 23307684
J Arthroplasty. 2019 Apr;34(4):717-722
pubmed: 30718172
Osteoarthritis Cartilage. 2017 Nov;25(11):1797-1803
pubmed: 28801208
Eff Clin Pract. 2001 Jul-Aug;4(4):172-7
pubmed: 11525104
Br J Haematol. 2001 Apr;113(1):24-31
pubmed: 11328275
J Arthroplasty. 2012 Jun;27(6):961-7
pubmed: 22608172
JBJS Rev. 2018 Feb;6(2):e6
pubmed: 29485516
J Arthroplasty. 2019 Sep;34(9):1938-1945
pubmed: 31155457
Int Orthop. 2008 Jun;32(3):339-43
pubmed: 17333185

Auteurs

Michele Palazzuolo (M)

Department of Orthopedic Surgery, Lausanne University Hospital - CHUV, Lausanne, Switzerland.

Alexander Antoniadis (A)

Department of Orthopedic Surgery, Lausanne University Hospital - CHUV, Lausanne, Switzerland.

Jaad Mahlouly (J)

Department of Orthopedic Surgery, Lausanne University Hospital - CHUV, Lausanne, Switzerland.

Julien Wegrzyn (J)

Department of Orthopedic Surgery, Lausanne University Hospital - CHUV, Lausanne, Switzerland. julien.wegrzyn@chuv.ch.
Hôpital Orthopédique, Centre Hospitalier Universitaire Vaudois - CHUV, Avenue Pierre Decker, 4, CH-1011, Lausanne, Switzerland. julien.wegrzyn@chuv.ch.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH