Is low anti-Mullerian hormone (AMH) level a risk factor of miscarriage in women <37 years old undergoing
Anti-mullerian Hormone
In Vitro Fertilization
diminished ovarian reserve
miscarriage
pregnancy loss
spontaneous abortion
Journal
Human fertility (Cambridge, England)
ISSN: 1742-8149
Titre abrégé: Hum Fertil (Camb)
Pays: England
ID NLM: 100888143
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
pubmed:
16
1
2021
medline:
28
9
2022
entrez:
15
1
2021
Statut:
ppublish
Résumé
Anti-Mullerian Hormone (AMH) is considered to be one of the most relevant markers of ovarian reserve. However, its association with oocyte quality, pregnancy occurrence and evolution remain to be further investigated. The objective of this study was to compare miscarriage rate after fresh blastocyst(s) transfer in young women (<37 years old) with or without diminished ovarian reserve (DOR), as reflected by low serum AMH levels. This monocentric retrospective study was conducted in 669 women undergoing 1,891 blastocyst transfers. Patients were divided into 2 groups: (1) 190 transfers performed in 106 women with a 'low' serum AMH (< 10th percentile) (i.e. AMH < 0.85 ng/mL); and (2) 961 transfers performed in 563 patients with a 'normal' serum AMH (25th-75th percentile) (i.e. AMH 1.4-4 ng/mL). Miscarriage rate was comparable in both groups (9.5 and 6.8% respectively;
Identifiants
pubmed: 33448232
doi: 10.1080/14647273.2021.1873431
doi:
Substances chimiques
Anti-Mullerian Hormone
80497-65-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM