Acidity, fluoride and silver ion concentrations in silver diamine fluoride solutions: a pilot study.
Dental caries
fluoride
pH
silver
silver diamine fluoride
Journal
Australian dental journal
ISSN: 1834-7819
Titre abrégé: Aust Dent J
Pays: Australia
ID NLM: 0370612
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
accepted:
04
01
2021
pubmed:
16
1
2021
medline:
28
5
2021
entrez:
15
1
2021
Statut:
ppublish
Résumé
There has been renewed interest in the use of silver diamine fluoride (SDF) for the management of carious lesions in high-risk groups. Previous studies have found a difference in clinical efficacy among different concentrations of SDF and discrepancies between ionic concentrations of fluoride (F) and silver (Ag) in SDF preparations. The aim of this study was to measure the free F, Ag ion concentrations and pH of a variety of commercially available SDF preparations. Seven SDF products used globally were evaluated for F and Ag ion concentrations using a calibrated ion-selective electrode and optical emission spectrometry respectively. Acidity was determined with a pH electrode. The 30% SDF solution contained almost half the F concentration and a much higher Ag concentration than expected (16 343 ppmF and 246 000 ppmAg). Comparatively, the mean F concentration of the remaining six 38% solutions was 74 802 ppm (expected mean 44 800 ppm) ranging from 36 457 ppm to 120 760 ppm. The mean Ag concentration was 326 000 ppm (expected mean 253 870 ppm) and ranged from 246 000 ppm to 425 451 ppm. All solutions were found to be neutral or mildly alkaline in nature (pH 7-10.3). Wide variations between claimed and measured F and Ag ion concentrations exist among the different brands of commercially available SDF products.
Sections du résumé
BACKGROUND
There has been renewed interest in the use of silver diamine fluoride (SDF) for the management of carious lesions in high-risk groups. Previous studies have found a difference in clinical efficacy among different concentrations of SDF and discrepancies between ionic concentrations of fluoride (F) and silver (Ag) in SDF preparations. The aim of this study was to measure the free F, Ag ion concentrations and pH of a variety of commercially available SDF preparations.
METHODS
Seven SDF products used globally were evaluated for F and Ag ion concentrations using a calibrated ion-selective electrode and optical emission spectrometry respectively. Acidity was determined with a pH electrode.
RESULTS
The 30% SDF solution contained almost half the F concentration and a much higher Ag concentration than expected (16 343 ppmF and 246 000 ppmAg). Comparatively, the mean F concentration of the remaining six 38% solutions was 74 802 ppm (expected mean 44 800 ppm) ranging from 36 457 ppm to 120 760 ppm. The mean Ag concentration was 326 000 ppm (expected mean 253 870 ppm) and ranged from 246 000 ppm to 425 451 ppm. All solutions were found to be neutral or mildly alkaline in nature (pH 7-10.3).
CONCLUSIONS
Wide variations between claimed and measured F and Ag ion concentrations exist among the different brands of commercially available SDF products.
Substances chimiques
Cariostatic Agents
0
Fluorides, Topical
0
Quaternary Ammonium Compounds
0
Silver Compounds
0
Sodium Fluoride
8ZYQ1474W7
silver diamine fluoride
DDU19UEV1Y
Fluorides
Q80VPU408O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
188-193Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : CommentIn
Informations de copyright
© 2021 Australian Dental Association.
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