[
Adult
Aged
Female
Fluorodeoxyglucose F18
/ chemistry
Gadolinium
/ chemistry
Head and Neck Neoplasms
/ diagnostic imaging
Humans
Lymph Nodes
/ diagnostic imaging
Lymphatic Metastasis
/ diagnostic imaging
Magnetic Resonance Imaging
/ methods
Male
Middle Aged
Multimodal Imaging
Positron-Emission Tomography
/ methods
Radiopharmaceuticals
/ chemistry
Retrospective Studies
Squamous Cell Carcinoma of Head and Neck
/ diagnostic imaging
HNSCC
Lymph nodes
PET/MRI
Journal
Annals of nuclear medicine
ISSN: 1864-6433
Titre abrégé: Ann Nucl Med
Pays: Japan
ID NLM: 8913398
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
12
10
2020
accepted:
04
12
2020
pubmed:
18
1
2021
medline:
15
10
2021
entrez:
17
1
2021
Statut:
ppublish
Résumé
To compare the accuracy of contrast-enhanced MRI using established dimensional and morphological criteria versus integrated [ We retrospectively reviewed 26 patients with histologically proven HNSCC who underwent gadolinium-enhanced [ Out of 865 lymph nodes, 35 were malignant at histopathology (3 with micro-metastases). Sensitivity and specificity were 48.6% and 99.5% for MRI using dimensional criteria; 60.0% and 99.6% for MRI using morphological criteria; 60.0% and 99.4% for MRI using both; and 74.3% and 97.6% for PET using MR as anatomic localization. The area under the ROC curve was higher for PET and MRI localization (0.859) than for MRI using dimensional (0.740; p < 0.05), or morphological (0.798; p < 0.05), or both criteria (0.797; p < 0.05). PET/MR using a PET SUVmax cutoff of 5.7 combined with MRI using dimensional and/or morphological criteria reached high values for accuracy (98.2%), NPV (98.2%), and PPV (95.2%). Compared with traditional contrast-enhanced MRI or PET alone, integrated PET/MRI could improve diagnostic accuracy in detecting metastatic lymph nodes in patients with HNSCC.
Identifiants
pubmed: 33454923
doi: 10.1007/s12149-020-01565-5
pii: 10.1007/s12149-020-01565-5
doi:
Substances chimiques
Radiopharmaceuticals
0
Fluorodeoxyglucose F18
0Z5B2CJX4D
Gadolinium
AU0V1LM3JT
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
260-269Références
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