The Effect of Counterions in Hydrophobic Ion Pairs on Oral Bioavailability of Exenatide.

Administration, Oral Animals Biological Availability Exenatide Hydrophobic and Hydrophilic Interactions Male Rats Rats, Sprague-Dawley
exenatide hydrophobic ion pairing (HIP) oral peptide delivery self-emulsifying drug delivery system (SEDDS)

Journal

ACS biomaterials science & engineering
ISSN: 2373-9878
Titre abrégé: ACS Biomater Sci Eng
Pays: United States
ID NLM: 101654670

Informations de publication

Date de publication:
14 09 2020
Historique:
entrez: 18 1 2021
pubmed: 19 1 2021
medline: 15 5 2021
Statut: ppublish

Résumé

The aim of this study was to evaluate the potential of

Identifiants

DOI: 10.1021/acsbiomaterials.0c00637 PMID: 33455296
pubmed: 33455296
doi: 10.1021/acsbiomaterials.0c00637
doi:

Substances chimiques

Exenatide 9P1872D4OL

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5032-5039

Auteurs

Thi Nhu Quynh Phan (TNQ)

Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, 6020 Innsbruck, Austria.
Faculty of Pharmacy, University of Medicine and Pharmacy, Hue University, 530000 Hue, Thua Thien Hue, Viet Nam.

Ruba Ismail (R)

Institute of Pharmaceutical Technology and Regulatory Affairs, Institute of Pharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Institute of Pharmaceutical Technology and Regulatory Affairs, Interdisciplinary Centre of Excellence, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.

Bao Le-Vinh (B)

Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, 6020 Innsbruck, Austria.
Department of Industrial Pharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000 Ho Chi Minh City, Viet Nam.

Sergey Zaichik (S)

Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, 6020 Innsbruck, Austria.

Flavia Laffleur (F)

Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, 6020 Innsbruck, Austria.
ORCID: 0000-0002-2827-6741

Andreas Bernkop-Schnürch (A)

Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, 6020 Innsbruck, Austria.
ORCID: 0000-0003-4187-8277

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Classifications MeSH

questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Voies d'administration de substances chimiques et des médicaments › Administration par voie orale › The Effect of Counterions in Hydrophobic Ion...
questionsmedicales.fr › Eucaryotes › Animaux › The Effect of Counterions in Hydrophobic Ion...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Biodisponibilité › The Effect of Counterions in Hydrophobic Ion...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Exénatide › The Effect of Counterions in Hydrophobic Ion...
questionsmedicales.fr › Phénomènes chimiques › Interactions hydrophobes et hydrophiles › The Effect of Counterions in Hydrophobic Ion...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › The Effect of Counterions in Hydrophobic Ion...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Sprague-Dawley › The Effect of Counterions in Hydrophobic Ion...