Arg-Glu-Asp-Val Peptide Immobilized on an Acellular Graft Surface Inhibits Platelet Adhesion and Fibrin Clot Deposition in a Peptide Density-Dependent Manner.

Animals Endothelial Cells Fibrin Oligopeptides Peptides Swine Swine, Miniature
REDV peptide acellular graft fibrin clot deposition silane coupling agent

Journal

ACS biomaterials science & engineering
ISSN: 2373-9878
Titre abrégé: ACS Biomater Sci Eng
Pays: United States
ID NLM: 101654670

Informations de publication

Date de publication:
13 04 2020
Historique:
entrez: 18 1 2021
pubmed: 19 1 2021
medline: 11 5 2021
Statut: ppublish

Résumé

Acellular blood vessels possess high potential to be used as tissue-engineered vascular scaffolds. Previously, a high patency was achieved for an Arg-Glu-Asp-Val (REDV) peptide-immobilized small-diameter acellular graft in a minipig model. Results revealed the potential of the peptide to capture a circulating cell and also to suppress fibrin clot deposition. Here, the effect of REDV peptide density on the blood response under

Identifiants

DOI: 10.1021/acsbiomaterials.0c00078 PMID: 33455328
pubmed: 33455328
doi: 10.1021/acsbiomaterials.0c00078
doi:

Substances chimiques

Oligopeptides 0
Peptides 0
arginyl-glutamyl-aspartyl-valine 0
Fibrin 9001-31-4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2050-2061

Auteurs

Atsushi Mahara (A)

Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Kishibe Shim-machi, Suita, Osaka 564-8565, Japan.
ORCID: 0000-0002-4075-6019

Kentaro Kojima (K)

Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Kishibe Shim-machi, Suita, Osaka 564-8565, Japan.
Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamatecho, Suita, Osaka 565-8680, Japan.

Yoshiaki Hirano (Y)

Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamatecho, Suita, Osaka 565-8680, Japan.

Tetsuji Yamaoka (T)

Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Kishibe Shim-machi, Suita, Osaka 564-8565, Japan.
ORCID: 0000-0003-0225-2407

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Arg-Glu-Asp-Val Peptide Immobilized on an...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › Arg-Glu-Asp-Val Peptide Immobilized on an...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Fibrine › Arg-Glu-Asp-Val Peptide Immobilized on an...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › Arg-Glu-Asp-Val Peptide Immobilized on an...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Arg-Glu-Asp-Val Peptide Immobilized on an...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Arg-Glu-Asp-Val Peptide Immobilized on an...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Sus scrofa › Porc miniature › Arg-Glu-Asp-Val Peptide Immobilized on an...