Employing a systematic approach to biobanking and analyzing clinical and genetic data for advancing COVID-19 research.


Journal

European journal of human genetics : EJHG
ISSN: 1476-5438
Titre abrégé: Eur J Hum Genet
Pays: England
ID NLM: 9302235

Informations de publication

Date de publication:
05 2021
Historique:
received: 24 07 2020
accepted: 25 11 2020
revised: 27 10 2020
pubmed: 19 1 2021
medline: 18 5 2021
entrez: 18 1 2021
Statut: ppublish

Résumé

Within the GEN-COVID Multicenter Study, biospecimens from more than 1000 SARS-CoV-2 positive individuals have thus far been collected in the GEN-COVID Biobank (GCB). Sample types include whole blood, plasma, serum, leukocytes, and DNA. The GCB links samples to detailed clinical data available in the GEN-COVID Patient Registry (GCPR). It includes hospitalized patients (74.25%), broken down into intubated, treated by CPAP-biPAP, treated with O

Identifiants

pubmed: 33456056
doi: 10.1038/s41431-020-00793-7
pii: 10.1038/s41431-020-00793-7
pmc: PMC7811682
doi:

Types de publication

Clinical Trial Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

745-759

Investigateurs

Francesca Montagnani (F)
Laura Di Sarno (L)
Andrea Tommasi (A)
Maria Palmieri (M)
Susanna Croci (S)
Arianna Emiliozzi (A)
Massimiliano Fabbiani (M)
Barbara Rossetti (B)
Giacomo Zanelli (G)
Laura Bergantini (L)
Miriana D'Alessandro (M)
Paolo Cameli (P)
David Bennet (D)
Federico Anedda (F)
Simona Marcantonio (S)
Sabino Scolletta (S)
Federico Franchi (F)
Maria Antonietta Mazzei (MA)
Susanna Guerrini (S)
Edoardo Conticini (E)
Luca Cantarini (L)
Bruno Frediani (B)
Danilo Tacconi (D)
Chiara Spertilli (C)
Marco Feri (M)
Alice Donati (A)
Raffaele Scala (R)
Luca Guidelli (L)
Genni Spargi (G)
Marta Corridi (M)
Cesira Nencioni (C)
Leonardo Croci (L)
Gian Piero Caldarelli (GP)
Maurizio Spagnesi (M)
Paolo Piacentini (P)
Maria Bandini (M)
Elena Desanctis (E)
Silvia Cappelli (S)
Anna Canaccini (A)
Agnese Verzuri (A)
Valentina Anemoli (V)
Agostino Ognibene (A)
Massimo Vaghi (M)
Antonella D'Arminio Monforte (A)
Esther Merlini (E)
Mario U Mondelli (MU)
Stefania Mantovani (S)
Serena Ludovisi (S)
Massimo Girardis (M)
Sophie Venturelli (S)
Marco Sita (M)
Andrea Cossarizza (A)
Andrea Antinori (A)
Alessandra Vergori (A)
Stefano Rusconi (S)
Matteo Siano (M)
Arianna Gabrieli (A)
Agostino Riva (A)
Daniela Francisci (D)
Elisabetta Schiaroli (E)
Pier Giorgio Scotton (PG)
Francesca Andretta (F)
Sandro Panese (S)
Renzo Scaggiante (R)
Francesca Gatti (F)
Saverio Giuseppe Parisi (SG)
Francesco Castelli (F)
Maria Eugenia Quiros-Roldan (ME)
Paola Magro (P)
Isabella Zanella (I)
Matteo Della Monica (M)
Carmelo Piscopo (C)
Mario Capasso (M)
Roberta Russo (R)
Immacolata Andolfo (I)
Achille Iolascon (A)
Giuseppe Fiorentino (G)
Massimo Carella (M)
Marco Castori (M)
Giuseppe Merla (G)
Filippo Aucella (F)
Pamela Raggi (P)
Carmen Marciano (C)
Rita Perna (R)
Matteo Bassetti (M)
Antonio Di Biagio (A)
Maurizio Sanguinetti (M)
Luca Masucci (L)
Chiara Gabbi (C)
Serafina Valente (S)
Ilaria Meloni (I)
Maria Antonietta Mencarelli (MA)
Caterina Lo Rizzo (CL)
Elena Bargagli (E)
Marco Mandalà (M)
Alessia Giorli (A)
Lorenzo Salerni (L)
Patrizia Zucchi (P)
Pierpaolo Parravicini (P)
Elisabetta Menatti (E)
Stefano Baratti (S)
Tullio Trotta (T)
Ferdinando Giannattasio (F)
Gabriella Coiro (G)
Fabio Lena (F)
Domenico A Coviello (DA)
Cristina Mussini (C)
Giancarlo Bosio (G)
Sandro Mancarella (S)
Luisa Tavecchia (L)

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Auteurs

Sergio Daga (S)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Chiara Fallerini (C)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Margherita Baldassarri (M)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Francesca Fava (F)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.

Floriana Valentino (F)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Gabriella Doddato (G)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Elisa Benetti (E)

Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Simone Furini (S)

Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Annarita Giliberti (A)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Rossella Tita (R)

Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.

Sara Amitrano (S)

Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.

Mirella Bruttini (M)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.

Ilaria Meloni (I)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Anna Maria Pinto (AM)

Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.

Francesco Raimondi (F)

Scuola Normale Superiore, Pisa, Italy.

Alessandra Stella (A)

CNR-Consiglio Nazionale delle Ricerche, Istituto di Biologia e Biotecnologia Agraria (IBBA), Milano, Italy.

Filippo Biscarini (F)

CNR-Consiglio Nazionale delle Ricerche, Istituto di Biologia e Biotecnologia Agraria (IBBA), Milano, Italy.
ERCEA (European Research Council Executive Agency), Bruxelles, Belgium.

Nicola Picchiotti (N)

University of Siena, DIISM- SAILAB, Siena, Italy.
Department of Mathematics, University of Pavia, Pavia, Italy.

Marco Gori (M)

University of Siena, DIISM- SAILAB, Siena, Italy.
Université Côte d'Azur, Inria, CNRS, I3S, Maasai, Italy.

Pietro Pinoli (P)

Department of Electronics, Information and Bioengineering (DEIB), Politecnico di Milano, Milano, Italy.

Stefano Ceri (S)

Department of Electronics, Information and Bioengineering (DEIB), Politecnico di Milano, Milano, Italy.

Maurizio Sanarico (M)

Independent Data Scientist, Milan, Italy.

Francis P Crawley (FP)

Good Clinical Practice Alliance-Europe (GCPA) and Strategic Initiative for Developing Capacity in Ethical Review-Europe (SIDCER), Brussels, Belgium.
ERCEA (European Research Council Executive Agency), Bruxelles, Belgium.

Giovanni Birolo (G)

Department of Medical Sciences, University of Turin, Turin, Italy.

Alessandra Renieri (A)

Medical Genetics, University of Siena, Siena, Italy. alessandra.renieri@unisi.it.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy. alessandra.renieri@unisi.it.
Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy. alessandra.renieri@unisi.it.

Francesca Mari (F)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.

Elisa Frullanti (E)

Medical Genetics, University of Siena, Siena, Italy.
Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

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