Changes in Functional Connectivity of Specific Cerebral Regions in Patients with Toothache: A Resting-State Functional Magnetic Resonance Imaging Study.
Journal
Disease markers
ISSN: 1875-8630
Titre abrégé: Dis Markers
Pays: United States
ID NLM: 8604127
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
11
2020
revised:
17
12
2020
accepted:
21
12
2020
entrez:
18
1
2021
pubmed:
19
1
2021
medline:
6
10
2021
Statut:
epublish
Résumé
In order to further study the changes of cerebral functional connectivity in patients with toothache (TA), this study used the resting-state functional magnetic resonance imaging (rs-fMRI) technique and degree centrality (DC) analysis method. Eighteen TA patients (8 males, 10 females) and 18 healthy individuals of similar age, sex, and educational levels were recruited as healthy controls (HCs) to take part in the study, and all underwent rs-fMRI examination. And DC technology was used to compare the state of their cerebral spontaneous functional activity. In order to compare the average DC values of the TA group and HC group, we used independent two-sample The TA group showed higher DC values in the right lingual gyrus (RLG), right precentral gyrus, and left middle temporal gyrus (LMTG) than HCs. Moreover, ROC curve analysis indicated that the area under the curve (AUC) of each cerebral region studied had high accuracy. In addition, linear analysis indicated that the DC values of the RLG were positively correlated with the Hospital Anxiety and Depression Scale (HADS) ( TA generates abnormal changes in the intrinsic activity patterns of pain-related and vision-related areas of the cerebral cortex, which will be beneficial to reveal the underlying neuropathic mechanisms.
Identifiants
pubmed: 33456630
doi: 10.1155/2020/6683161
pmc: PMC7785343
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
6683161Informations de copyright
Copyright © 2020 Shi-Nan Wu et al.
Déclaration de conflit d'intérêts
The authors declare no potential conflicts of interest.
Références
PLoS One. 2014 May 12;9(5):e97502
pubmed: 24821143
J Dent Res. 2012 Feb;91(2):156-60
pubmed: 22157099
Eur J Radiol. 2015 Nov;84(11):2287-95
pubmed: 26321490
Elife. 2018 Dec 21;7:
pubmed: 30574868
Neuron. 2007 Aug 2;55(3):377-91
pubmed: 17678852
Brain Lang. 2018 Feb - Mar;177-178:23-36
pubmed: 29421269
Eur J Radiol. 2015 Jul;84(7):1318-24
pubmed: 25963506
PLoS One. 2015 Oct 27;10(10):e0141389
pubmed: 26506229
Eur J Pain. 2011 Feb;15(2):124-31
pubmed: 20609605
J Affect Disord. 2017 Jun;215:111-117
pubmed: 28319687
Neural Plast. 2019 Apr 24;2019:7349894
pubmed: 31178903
J Cogn Neurosci. 2018 May;30(5):621-633
pubmed: 29393716
Hua Xi Kou Qiang Yi Xue Za Zhi. 2006 Apr;24(2):121-4
pubmed: 16704087
Neural Plast. 2020 Apr 25;2020:5701042
pubmed: 32377180
Evid Based Complement Alternat Med. 2012;2012:934085
pubmed: 23326294
Evid Based Complement Alternat Med. 2015;2015:210120
pubmed: 26161117
J Affect Disord. 2019 May 15;251:78-85
pubmed: 30909161
Curr Opin Anaesthesiol. 2013 Oct;26(5):588-93
pubmed: 23995063
Neurosci Res. 2011 Jul;70(3):285-93
pubmed: 21514332
J Orofac Pain. 2010 Fall;24(4):379-90
pubmed: 21197510
Dtsch Zahnarztl Z. 1991 Feb;46(2):101-8
pubmed: 1814700
Ophthalmic Physiol Opt. 2016 May;36(3):240-65
pubmed: 27112223
Eur J Oral Sci. 2009 Dec;117(6):711-9
pubmed: 20121935
J Cogn Neurosci. 2013 Oct;25(10):1664-77
pubmed: 23767923
Neuroimage. 2011 Jan 15;54(2):875-91
pubmed: 20817103
Hum Brain Mapp. 2001 Dec;14(4):210-7
pubmed: 11668652
Am J Phys Med Rehabil. 2017 Apr;96(4):253-259
pubmed: 28301866
Front Hum Neurosci. 2016 Mar 15;10:107
pubmed: 27014038
Neurosci Lett. 2019 Nov 1;712:134500
pubmed: 31557522
Eur J Oral Sci. 2009 Feb;117(1):27-33
pubmed: 19196315
Neurosurgery. 2018 Mar 1;82(3):350-358
pubmed: 28419330
J Pain Res. 2018 Apr 20;11:843-850
pubmed: 29719418
Prog Neuropsychopharmacol Biol Psychiatry. 2020 Apr 20;99:109824
pubmed: 31765713
J Neurosci. 2018 Sep 5;38(36):7787-7799
pubmed: 30037832
Chin Med J (Engl). 2015 Dec 5;128(23):3178-84
pubmed: 26612293
Acta Psychiatr Scand. 2018 Jun;137(6):491-502
pubmed: 29457245
J Headache Pain. 2019 Mar 25;20(1):29
pubmed: 30909865
Pain. 2010 Jun;149(3):529-538
pubmed: 20382476
Am J Phys Med Rehabil. 2001 Oct;80(10):717
pubmed: 11562551
Front Neurosci. 2019 Apr 30;13:415
pubmed: 31114477
PLoS One. 2013 Sep 12;8(9):e73670
pubmed: 24069220
Behav Brain Res. 2017 May 30;326:132-138
pubmed: 28126471
Pain. 2006 Feb;120(3):286-296
pubmed: 16427198
Mol Med Rep. 2017 Dec;16(6):8295-8300
pubmed: 28983610
Behav Neurol. 2019 Jan 14;2019:4139404
pubmed: 30733834
Pain. 2012 Oct;153(10):2140-2151
pubmed: 22883925