[Sorting and detection of COVID-19 by low-dose thoracic CT scan in patients consulting the radiology department of Fann hospital (Dakar-Senegal)].
Tri et détection du COVID-19 par TDM thoracique low-dose chez des patients tout-venant au service de radiologie de l´hôpital de Fann (Dakar-Sénégal).
COVID-19
CT scan
PCR
Senegal
ground-glass opacity
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2020
2020
Historique:
received:
18
09
2020
accepted:
19
09
2020
entrez:
18
1
2021
pubmed:
19
1
2021
medline:
25
2
2021
Statut:
epublish
Résumé
COVID-19 has spread rapidly since its emergence in China and is currently a global health issue. Its definitive diagnosis is made by PCR on nasopharyngeal swabs. However, this diagnostic test has low sensitivity with delayed results. Hence, thoracic computed tomography represents an interesting alternative. The aims of this study were to assess the frequency of computed tomography (CT) lesions suggestive of COVID-19 and to compare the results of CT and PCR test. a prospective study carried out over15 working days and involved 47 patients. These patients were recruited based on the presence of at least 2 clinical signs of COVID-19. Chest CT without contrast according to the "LOW-DOSE" protocol was performed. A PCR test on nasopharyngeal swabs was done in patients with signs suggestive of COVID on CT. A serological test was performed in case of a discrepancy between the CT and PCR results. thoracic CT was abnormal in 38 patients and normal in 9 patients. Lesions suggestive of COVID-19 have been identified in 32 patients. Two patients had lesions of non-specific pneumonia. Tuberculosis lesions were visualized in 3 patients. One patient had lesions of interstitial pneumonia. The mean DLP was 59 mGy.cm with extremes of 25 and 95 mGy.cm. Ground-glass opacity was present in 100% of COVID-19 suspects on CT. The results of the PCR test were the same than CT in 12 patients. The positive predictive value for CT was 37.5%. In 20 patients with COVID lesions on CT, the PCR test was negative with a false positive rate of 62.5%. In the patients with negative PCR test, 4 had a serological test for COVID-19 and this test was positive in 3. low-dose chest CT can reduce radiation exposure in COVID-19 patients who are at risk of cumulative dose due to repetitive exam. CT can identify lesions suggestive of COVID-19. It also enables the triage of patients by identifying other diagnoses.
Identifiants
pubmed: 33456646
doi: 10.11604/pamj.supp.2020.37.22.26140
pii: PAMJ-SUPP-37-1-22
pmc: PMC7796847
doi:
Types de publication
Comparative Study
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
22Informations de copyright
Copyright: Ibrahima Niang et al.
Déclaration de conflit d'intérêts
Les auteurs ne déclarent aucun conflit d’intérêts.
Références
Emerg Radiol. 2020 Dec;27(6):601-605
pubmed: 32390122
Euro Surveill. 2020 Jan;25(3):
pubmed: 31992387
Pan Afr Med J. 2020 Aug 09;35(Suppl 2):138
pubmed: 33193953
Acad Radiol. 2020 May;27(5):609-613
pubmed: 32204990
Radiol Infect Dis. 2020 Jun;7(2):51-54
pubmed: 32309528
Radiol Cardiothorac Imaging. 2020 Apr 21;2(2):e200196
pubmed: 33778576
Int J Infect Dis. 2020 Jul;96:157-162
pubmed: 32423888
Eur J Radiol. 2020 May;126:108961
pubmed: 32229322
Pan Afr Med J. 2020 Jul 01;35(Suppl 2):98
pubmed: 33623622
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Auris Nasus Larynx. 2020 Aug;47(4):565-573
pubmed: 32553562
Radiology. 2020 Aug;296(2):E115-E117
pubmed: 32073353
Radiology. 2006 Sep;240(3):828-34
pubmed: 16837668
Radiology. 2020 Aug;296(2):E32-E40
pubmed: 32101510
Radiology. 2020 Aug;296(2):E41-E45
pubmed: 32049601
Chest. 2020 Jul;158(1):106-116
pubmed: 32275978