Comparison of postoperative complications of ileal conduits versus orthotopic neobladders.

Bladder cancer (BC) complication ileal conduit (IC) neobladder (NB) radical cystectomy (RC)

Journal

Translational andrology and urology
ISSN: 2223-4691
Titre abrégé: Transl Androl Urol
Pays: China
ID NLM: 101581119

Informations de publication

Date de publication:
Dec 2020
Historique:
entrez: 18 1 2021
pubmed: 19 1 2021
medline: 19 1 2021
Statut: ppublish

Résumé

Radical cystectomy (RC) and urinary diversion (UD), with either an ileal conduit (IC) or an orthotopic neobladder (NB), is a complex surgery, in which various complications can occur. In this study, we compared postoperative complication rates after a RC and UD performed for the treatment of muscle-invasive bladder cancer or recurring high-risk non-muscle-invasive bladder cancer in our center. We retrospectively included 604 patients that underwent UDs from December 1996 to August 2015. Complications were classified by type and severity according to the Clavien-Dindo classification (CDC). Univariate and multivariate analyses were performed to identify predictive factors of short-term (≤30 d), intermediate-term (31-90 d), and long-term (>90 d) complications. Four hundred and forty-five (74%) and 159 (26%) patients received ICs and NBs, respectively. These groups had significantly different long-term complication rates (IC: 39.7% The increasing risk of short-term complications with increasing aCCI and ASA score can be used when counseling the patients who are planned to undergo a RC with UD. Patients that receive NBs should be informed of the increased risk of reoperations compared to an IC.

Sections du résumé

BACKGROUND BACKGROUND
Radical cystectomy (RC) and urinary diversion (UD), with either an ileal conduit (IC) or an orthotopic neobladder (NB), is a complex surgery, in which various complications can occur. In this study, we compared postoperative complication rates after a RC and UD performed for the treatment of muscle-invasive bladder cancer or recurring high-risk non-muscle-invasive bladder cancer in our center.
METHODS METHODS
We retrospectively included 604 patients that underwent UDs from December 1996 to August 2015. Complications were classified by type and severity according to the Clavien-Dindo classification (CDC). Univariate and multivariate analyses were performed to identify predictive factors of short-term (≤30 d), intermediate-term (31-90 d), and long-term (>90 d) complications.
RESULTS RESULTS
Four hundred and forty-five (74%) and 159 (26%) patients received ICs and NBs, respectively. These groups had significantly different long-term complication rates (IC: 39.7%
CONCLUSIONS CONCLUSIONS
The increasing risk of short-term complications with increasing aCCI and ASA score can be used when counseling the patients who are planned to undergo a RC with UD. Patients that receive NBs should be informed of the increased risk of reoperations compared to an IC.

Identifiants

pubmed: 33457228
doi: 10.21037/tau-20-713
pii: tau-09-06-2541
pmc: PMC7807350
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2541-2554

Informations de copyright

2020 Translational Andrology and Urology. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tau-20-713). The authors have no conflicts of interest to declare.

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Auteurs

Liesbeth Demaegd (L)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Maarten Albersen (M)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Tim Muilwijk (T)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Uros Milenkovic (U)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Lisa Moris (L)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Wouter Everaerts (W)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Hendrik Van Poppel (H)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Frank Van der Aa (F)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Steven Joniau (S)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Murat Akand (M)

Department of Urology, University Hospitals Leuven, Leuven, Belgium.
Department of Urology, School of Medicine, Selçuk University, Konya, Turkey.

Classifications MeSH