Effect of Watermelon Extract on Nerve Conduction Velocity, Memory, and T4 Level in Rats.

Citrullus hyperthyroidism memory neural conduction

Journal

Advanced biomedical research
ISSN: 2277-9175
Titre abrégé: Adv Biomed Res
Pays: India
ID NLM: 101586897

Informations de publication

Date de publication:
2020
Historique:
received: 29 12 2019
revised: 04 02 2020
accepted: 11 05 2020
entrez: 18 1 2021
pubmed: 19 1 2021
medline: 19 1 2021
Statut: epublish

Résumé

Watermelon is a fruit with the thirst-quenching effect and especially is consumed in summer. In this study, the effect of consumption of watermelon extract (in drinking water) on thyroid hormone level (TT4), animals' weight, water and food consumption, nerve conduction velocity (NCV), and memory in Wistar rats were investigated. Twenty-four male Wistar rats were divided into three groups: control, CT 1500 mg/kg, and CT 3000 mg/kg ( The results showed that animals' weight in both the treatment groups decreased compared to the control group ( Based on these finding, in spite of increase in food and water consumption in the treated groups, animal weight did not increase significantly. Impairment in memory and decrease in NCV were also occurred, but TT4 level was increased in animals treated with watermelon extract.

Sections du résumé

BACKGROUND BACKGROUND
Watermelon is a fruit with the thirst-quenching effect and especially is consumed in summer. In this study, the effect of consumption of watermelon extract (in drinking water) on thyroid hormone level (TT4), animals' weight, water and food consumption, nerve conduction velocity (NCV), and memory in Wistar rats were investigated.
MATERIALS AND METHODS METHODS
Twenty-four male Wistar rats were divided into three groups: control, CT 1500 mg/kg, and CT 3000 mg/kg (
RESULTS RESULTS
The results showed that animals' weight in both the treatment groups decreased compared to the control group (
CONCLUSION CONCLUSIONS
Based on these finding, in spite of increase in food and water consumption in the treated groups, animal weight did not increase significantly. Impairment in memory and decrease in NCV were also occurred, but TT4 level was increased in animals treated with watermelon extract.

Identifiants

pubmed: 33457336
doi: 10.4103/abr.abr_264_19
pii: ABR-9-53
pmc: PMC7792879
doi:

Types de publication

Journal Article

Langues

eng

Pagination

53

Informations de copyright

Copyright: © 2020 Advanced Biomedical Research.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

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Auteurs

Majid Jafari Nejad Bajestani (M)

Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Mahdi Yousefi (M)

Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Mousa-Al-Reza Hadjzadeh (MA)

Department of Physiology, School of Medicine Mashhad University of Medical Sciences, Mashhad, Iran.
Division of Neurocognitive Sciences, Psychiatry and Behavioural Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Mahmoud Hosseini (M)

Department of Physiology, School of Medicine Mashhad University of Medical Sciences, Mashhad, Iran.
Division of Neurocognitive Sciences, Psychiatry and Behavioural Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Ali Taghipour (A)

Department of Epidemiology and Biostatistics, Cancer Research Center, Social Determinants of Health Research Center, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

Shiba Yousefvand (S)

Department of Physiology, School of Medicine Mashhad University of Medical Sciences, Mashhad, Iran.

Classifications MeSH