In vivo dosimetry in external beam photon radiotherapy: Requirements and future directions for research, development, and clinical practice.

External beam radiotherapy with photon beams is a highly accurate treatment modality, but requires extensive quality assurance programs to confirm that radiation therapy will be or was administered appropriately. In vivo dosimetry (IVD) is an essential element of modern radiation therapy because it provides the ability to catch treatment delivery errors, assist in treatment adaptation, and record the actual dose delivered to the patient. However, for various reasons, its clinical implementation has been slow and limited. The purpose of this report is to stimulate the wider use of IVD for external beam radiotherapy, and in particular of systems using electronic portal imaging devices (EPIDs). After documenting the current IVD methods, this report provides detailed software, hardware and system requirements for

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© 2020 The Authors.

Déclaration de conflit d'intérêts

The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: I Olaciregui-Ruiz and B Mijnheer declare that their department licensed portal dosimetry software to Elekta Oncology Systems Ltd. for the development of the iViewDose product. This product is currently not commercially available. P Greer declares research collaborations with Varian Medical Systems. B McCurdy declares funded research collaborations on EPID dosimetry with Varian Medical Systems. N. Jornet declares that she is member of the European scientific advisory board of Sun Nuclear. F Verhaegen declares research collaborations and a patent on in vivo dosimetry with Varian Medical Systems.