Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field.

3D radiation dosimetry Magnetic resonance imaging guided radiotherapy

Journal

Physics and imaging in radiation oncology
ISSN: 2405-6316
Titre abrégé: Phys Imaging Radiat Oncol
Pays: Netherlands
ID NLM: 101704276

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 02 07 2020
revised: 02 10 2020
accepted: 05 10 2020
entrez: 18 1 2021
pubmed: 19 1 2021
medline: 19 1 2021
Statut: epublish

Résumé

The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of silicone-based 3D radiochromic dosimeters for photon irradiation in a magnetic field using a 0.35 T MRgRT system. We found a linear dose response up to 22.6 Gy and no significant dose-rate dependency as a function of depth. A difference in optical response was observed for dosimeters irradiated in a single compared to multiple fractions. The dosimeter showed clinical potential for verification of MRgRT delivery.

Identifiants

pubmed: 33458348
doi: 10.1016/j.phro.2020.10.003
pii: S2405-6316(20)30066-X
pmc: PMC7807676
doi:

Types de publication

Journal Article

Langues

eng

Pagination

81-84

Informations de copyright

© 2020 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

J Appl Clin Med Phys. 2019 Jul;20(7):87-99
pubmed: 31183949
Radiother Oncol. 2017 Dec;125(3):426-432
pubmed: 28964533
Phys Med Biol. 2018 Jun 07;63(11):11NT03
pubmed: 29762130
Med Phys. 2019 Jan;46(1):293-301
pubmed: 30341911
Phys Med Biol. 2017 Feb 21;62(4):N73-N89
pubmed: 28134130
Phys Med Biol. 2015 Feb 21;60(4):1543-63
pubmed: 25615261
Phys Med Biol. 2005 Nov 21;50(22):5251-61
pubmed: 16264251
Phys Med Biol. 2020 May 04;65(9):095003
pubmed: 32143198
Phys Med Biol. 2019 Sep 04;64(17):175013
pubmed: 31307018
Phys Med Biol. 2018 Aug 20;63(16):165014
pubmed: 30124200
Phys Med Biol. 2010 Mar 7;55(5):R1-63
pubmed: 20150687
Phys Med Biol. 2015 Jul 21;60(14):5557-70
pubmed: 26134268
Phys Med Biol. 2017 Jun 14;62(14):5612-5622
pubmed: 28467323
PLoS One. 2017 Jul 13;12(7):e0180970
pubmed: 28704443

Auteurs

Morten B Jensen (MB)

Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
Department of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.

Peter Balling (P)

Department of Physics and Astronomy, Aarhus University, Aarhus, Denmark.
Interdisciplinary Nanoscience Center, Aarhus University, Aarhus, Denmark.

Simon J Doran (SJ)

The Institute of Cancer Research, London, UK.

Jørgen B B Petersen (JBB)

Department of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.

Isak H Wahlstedt (IH)

Technical University of Denmark, Lyngby, Denmark.
Department of Clinical Oncology, Rigshospitalet, Copenhagen, Denmark.
Department of Oncology, Herlev and Gentofte Hospital, Copenhagen, Denmark.

Ludvig P Muren (LP)

Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
Department of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.

Classifications MeSH