Allyl isothiocyanate (AITC) activates nonselective cation currents in human cardiac fibroblasts: possible involvement of TRPA1.

Allyl isothiocyanate Human cardiac fibroblast Methylglyoxal Nonselective cation channels TRPA1 Transient receptor potential ankyrin 1

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 22 05 2020
revised: 11 08 2020
accepted: 18 12 2020
entrez: 18 1 2021
pubmed: 19 1 2021
medline: 19 1 2021
Statut: epublish

Résumé

The effects of allyl isothiocyanate (AITC), transient receptor potential ankyrin 1 (TRPA1) agonist, on cultured human cardiac fibroblasts were examined by measuring intracellular Ca

Identifiants

pubmed: 33458442
doi: 10.1016/j.heliyon.2020.e05816
pii: S2405-8440(20)32659-1
pmc: PMC7797518
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e05816

Informations de copyright

© 2020 The Author(s).

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Gaku Oguri (G)

Department of Cardiovascular Medicine, University of Tokyo, Tokyo 113-8655, Japan.

Toshiaki Nakajima (T)

Department of Cardiovascular Medicine, Dokkyo Medical University, Tochigi, 321-0293, Japan.

Hironobu Kikuchi (H)

Department of Cardiovascular Medicine, University of Tokyo, Tokyo 113-8655, Japan.

Shotaro Obi (S)

Department of Cardiovascular Medicine, Dokkyo Medical University, Tochigi, 321-0293, Japan.

Fumitaka Nakamura (F)

Teikyo University Chiba Medical Center, Ichihara, 299-0111, Chiba, Japan.

Issei Komuro (I)

Department of Cardiovascular Medicine, University of Tokyo, Tokyo 113-8655, Japan.

Classifications MeSH