Cyto-morphological and clinical approach to infections presenting with discharging sinuses mimicking malignancy.
FNAC
cytomorphology
discharging sinus
infections
malignancy
Journal
Diagnostic cytopathology
ISSN: 1097-0339
Titre abrégé: Diagn Cytopathol
Pays: United States
ID NLM: 8506895
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
19
05
2020
revised:
03
07
2020
accepted:
14
07
2020
entrez:
18
1
2021
pubmed:
19
1
2021
medline:
1
10
2021
Statut:
ppublish
Résumé
Discharging sinuses is a form of chronic unhealed infection that can present at any site due to a variety of infectious organisms. These discharging sinuses may be associated with mass lesions and lymphadenopathy to mimic some neoplastic processes. Identifying these infections with accuracy and promptness is essential, as the treatment regimens are specific. Fine-needle aspiration (FNA) of these lesions, along with appropriate cytochemical stains, aids in the rapid and precise diagnosis of these infections and excludes neoplasms at these sites. Also, material for culture and other studies can be obtained by FNA. This retrospective study was conducted in the Department of pathology from 2018 to 2020. A total of 179 patients with similar clinical presentation and confirmed infection on cytology were identified. On the evaluation of the requisition forms, 32 (18%) patients were identified with discharging sinus associated along with swelling. The five infections (32 cases) that were identified, included 18 cases of tuberculosis (56.25%) followed by 9 cases of actinomycosis (28.12%), 3 cases of pheohypomycosis (9.37%), and one case each of Nocardia (3.12%) and eumycetoma (3.12%) which presented as swelling with discharging sinus. Special stains were performed in all cases for confirmation. Histopathological/Microbiological correlation was done whenever available. Infections presenting as swelling with discharging sinuses mimicking malignancy can be diagnosed on FNAC with good accuracy.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1265-1272Informations de copyright
© 2020 Wiley Periodicals LLC.
Références
Al‐Obaida MI, Al‐Madi EM. Cutaneous draining sinus tract of odontogenic origin. Saudi Med J. 2019;40:292‐297.
Michaelides SA, Bablekos GD, Michailidis A‐R, Gkioxari E, Vgenopoulou S, Chorti M. Left lateral cervical mass with draining sinuses. Case Rep Med. 2019;2019:7838596.
Das DK. Fine‐needle aspiration cytology in the diagnosis of tuberculous lesions. Lab Med. 2000;31:625‐632.
Gajdács M, Urbán E, Terhes G. Microbiological and clinical aspects of cervicofacial actinomyces infections: an overview. Dent J (Basel). 2019;7(3):85. https://doi.org/10.3390/dj7030085
Fernandes H, D'souza CRS, Shekar JC, Marla NJ, Swethadri GK, Naik R. Cytodiagnosis of actinomycetoma. Diagn Cytopathol. 2009;37:506‐508.
Agnihotri M, Kothari K, Naik L. Primary actinomycosis of anterior abdominal wall: a rare occurrence, diagnosed on fine needle aspiration cytology. Indian J Pathol Microbiol. 2019;62:629‐630.
Gudivada V, Gochhait D, Bhandary C, Mishra N, Siddaraju N. Cutaneous nocardiosis with discharging sinus clinically mimicking tuberculosis diagnosed by cytology. Diagn Cytopathol. 2019;47:935‐938.
Maraki S, Chochlidakis S, Nioti E, Tselentis Y. Primary lymphocutaneous nocardiosis in an immunocompetent patient. Ann Clin Microbiol Antimicrob. 2004;3:24‐24.
Boiron P, Locci R, Goodfellow M, et al. Nocardia, nocardiosis and mycetoma. Med Mycol. 1998;36(Suppl 1):26‐37.
Afroz N, Khan N, Siddiqui FA, Rizvi M. Eumycetoma versus actinomycetoma: diagnosis on cytology. J Cytol. 2010;27:133‐135.
Hemalata M, Prasad S, Venkatesh K, R NS, Kumar SA. Cytological diagnosis of actinomycosis and eumycetoma: a report of two cases. Diagn Cytopathol. 2010;38:918‐920.
EL Hag IA, Fahal AH, Gasim ET. Fine needle aspiration cytology of mycetoma. Acta Cytol. 1996;40:461‐464.
Welsh O, Al‐Abdely HM, Salinas‐Carmona MC, Fahal AH. Mycetoma medical therapy. PLoS Negl Trop Dis. 2014;8:1‐8.
Behera B, Thomas E, Kumari R, Thappa DM, Jinkala S. Polymorphous presentation of subcutaneous phaeohyphomycosis: a rare occurrence. Int J Dermatol. 2017;57(2):e1‐e3.