Telomere length is heritable and genetically correlated with lifespan in a wild bird.
ageing
biomarker
birds
heritability
senescence
telomeres
Journal
Molecular ecology
ISSN: 1365-294X
Titre abrégé: Mol Ecol
Pays: England
ID NLM: 9214478
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
revised:
18
12
2020
received:
09
09
2020
accepted:
08
01
2021
pubmed:
19
1
2021
medline:
31
1
2023
entrez:
18
1
2021
Statut:
ppublish
Résumé
Telomeres are protective caps at the end of eukaryotic chromosomes that shorten with age and in response to stressful or resource-demanding conditions. Their length predicts individual health and lifespan across a wide range of animals, but whether the observed positive association between telomere length and lifespan is environmentally induced, or set at conception due to a shared genetic basis, has not been tested in wild animals. We applied quantitative genetic "animal models" to longitudinal telomere measurements collected over a 10-year period from individuals of a wild seabird (common tern; Sterna hirundo) with known pedigree. We found no variation in telomere shortening with age among individuals at the phenotypic and genetic level, and only a small permanent environmental effect on adult telomere length. Instead, we found telomere length to be highly heritable and strongly positively genetically correlated with lifespan. Such heritable differences between individuals that are set at conception may present a hitherto underappreciated component of variation in somatic state.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6297-6307Informations de copyright
© 2021 The Authors. Molecular Ecology published by John Wiley & Sons Ltd.
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