Recent advances on mycotic keratitis caused by dematiaceous hyphomycetes.
cornea
dematiaceous hyphomycetes
diagnosis
fungi
mycotic keratitis
treatment
Journal
Journal of applied microbiology
ISSN: 1365-2672
Titre abrégé: J Appl Microbiol
Pays: England
ID NLM: 9706280
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
revised:
31
12
2020
received:
21
08
2020
accepted:
14
01
2021
pubmed:
20
1
2021
medline:
16
10
2021
entrez:
19
1
2021
Statut:
ppublish
Résumé
Dematiaceous hyphomycetes (DH) are darkly pigmented fungi ubiquitously found all over the world as plant pathogens and saprophytes, and many of the members of this group have emerged as opportunistic pathogens. These fungi are responsible for a wide variety of infections including mycotic keratitis, which is considered as one of the major causes of corneal blindness, particularly in tropical and subtropical countries with an annual global burden of about 1 000 000 patients. The infection is more common in workers working in an outdoor environment. Moreover, trauma is found to be the most important predisposing cause of mycotic keratitis. Considerable delay in diagnosis and scarcity of effective pharmacological drugs are the major factors responsible for increased morbidity and visual impairment. Considering the crucial role of DH in mycotic keratitis, in the present review, we have focused on major DH with special emphasis on their pathogenicity, diagnosis and treatment strategies.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1652-1667Informations de copyright
© 2021 The Society for Applied Microbiology.
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