Predicting models of depression or complicated grief among bereaved family members of patients with cancer.
bereavement
cancer
complicated grief
depression
family caregivers
oncology
prediction
psycho-oncology
risk score
Journal
Psycho-oncology
ISSN: 1099-1611
Titre abrégé: Psychooncology
Pays: England
ID NLM: 9214524
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
07
01
2021
accepted:
11
01
2021
pubmed:
20
1
2021
medline:
25
2
2023
entrez:
19
1
2021
Statut:
ppublish
Résumé
To derive and validate a risk scoring system for predicting major depressive disorder (MDD) and complicated grief (CG) among bereaved family members of patients with cancer that is feasible for clinical use. We conducted a secondary analysis of two cross-sectional nationwide bereavement surveys in Japan. From a total of 17,312 bereaved family members of patients with cancer, 8618 and 8619 were randomly assigned to a derivation and a validation group. The Patient Health Questionnaire 9 (PHQ-9) and the Brief Grief Questionnaire (BGQ) were used to assess MDD (PHQ-9 score ≥ 10) and CG (BGQ score ≥ 8), respectively. We compared five models with potential predictive variables that could be easily obtained in daily practice and were included in the bereavement survey (i.e., sociodemographic data). The model which included variables such as the families' physical/mental health status and preparedness toward bereavement, in addition to their sociodemographic data, was considered modest for predicting the risk of both MDD and CG. The areas around the curve for MDD and CG were 0.74 (95% CI: 0.73-0.76) and 0.74 (95% CI: 0.72-0.75) and 0.78 (95% CI: 0.76-0.79) and 0.77 (95% CI: 0.76-0.79) in the derivation and validation groups, respectively. We developed a clinical risk score for predicting MDD and CG among bereaved family members of patients with cancer. However, further research is needed for external validation and assessment regarding its implementation in actual practice.
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1151-1159Informations de copyright
© 2021 John Wiley & Sons Ltd.
Références
Maciejewski PK, Zhang B, Block SD, Prigerson HG. An empirical examination of the stage theory of grief. J Am Med Assoc. 2007;297(7):716-723.
Boelen PA, van den Bout J. Complicated grief and uncomplicated grief are distinguishable constructs. Psychiatry Res 2008;157(1-3):311-314.
Stroebe M, Schut H, Stroebe W. Health outcomes of bereavement. Lancet. 2007;370(9603):1960-1973.
Aoyama M, Sakaguchi Y, Morita T, et al. Factors associated with possible complicated grief and major depressive disorders. Psychooncology. 2018;27(3):915-921.
Agnew A, Manktelow R, Taylor B, Jones L. Bereavement needs assessment in specialist palliative care: a review of the literature. Palliat Med. 2010;24(1):46-59.
Maccallum F, Bryant RA. Autobiographical memory following cognitive behaviour therapy for complicated grief. J Behav Ther Exp Psychiatry. 2011;42(1):26-31.
Forte AL, Hill M, Pazder R, Feudtner C. Bereavement care interventions: a systematic review. BMC Palliat Care. 2004;3(1):3.
Boelen PA, de Keijser J, van den Hout MA, van den Bout J. Treatment of complicated grief: a comparison between cognitive-behavioral therapy and supportive counseling. J Consult Clin Psychol. 2007;75(2):277-284.
Maciejewski PK, Prigerson HG. Prolonged, but not complicated, grief is a mental disorder. Br J Psychiatry. 2017;211(4):189-191.
Bui E, Simon NM, Robinaugh DJ, et al. Periloss dissociation, symptom severity, and treatment response in complicated grief. Depress Anxiety. 2013;30(2):123-128.
Kissane DW, Zaider TI, Li Y, et al. Randomized controlled trial of family therapy in advanced cancer continued into bereavement. J Clin Oncol. 2016;34(16):1921-1927.
Breen LJ, Aoun SM, O'Connor M, Rumbold B. Bridging the gaps in palliative care bereavement support: an international perspective. Death Stud. 2014;38(1-5):54-61.
Aoun SM, Rumbold B, Howting D, Bolleter A, Breen LJ. Bereavement support for family caregivers: the gap between guidelines and practice in palliative care. PLoS One. 2017;12(10):e0184750.
Prigerson HG, Horowitz MJ, Jacobs SC, et al. Prolonged grief disorder: psychometric validation of criteria proposed for DSM-V and ICD-11. PLoS Med. 2009;6(8):e1000121.
Miyajima K, Fujisawa D, Yoshimura K, et al. Association between quality of end-of-life care and possible complicated grief among bereaved family members. J Palliat Med. 2014;17(9):1025-1031.
Fujisawa D, Miyashita M, Nakajima S, Ito M, Kato M, Kim Y. Prevalence and determinants of complicated grief in general population. J Affect Disord. 2010;127(1-3):352-358.
van der Houwen K, Stroebe M, Stroebe W, Schut H, van den Bout J, Wijngaards-de Meij L. Risk factors for bereavement outcome: a multivariate approach. Death Stud. 2010;34(3):195-220.
Sealey M, Breen LJ, O'Connor M, Aoun SM. A scoping review of bereavement risk assessment measures: implications for palliative care. Palliat Med. 2015;29(7):577-589.
Rose C, Wainwright W, Downing M, Lesperance M. Inter-rater reliability of the bereavement risk assessment tool. Palliat Support Care. 2011;9(2):153-164.
Kristjanson LJ, Cousins K, Smith J, Lewin G. Evaluation of the Bereavement Risk Index (BRI): a community hospice care protocol. Int J Palliat Nurs. 2005;11(12):612-618.
Roberts K, Holland J, Prigerson HG, et al. Development of the Bereavement Risk Inventory and Screening Questionnaire (BRISQ): item generation and expert panel feedback. Palliat Support Care. 2017;15(1):57-66.
Masukawa K, Aoyama M, Morita T, et al. The Japan hospice and palliative evaluation study 4: a cross-sectional questionnaire survey. BMC Palliat Care. 2018;17(1):66.
Hatano Y, Aoyama M, Morita T, et al. The relationship between cancer patients' place of death and bereaved caregivers' mental health status. Psychooncology. 2017;26(11):1959-1964.
Aoyama M, Morita T, Kizawa Y, Tsuneto S, Shima Y, Miyashita M. The Japan HOspice and palliative care evaluation study 3: study design, characteristics of participants and participating institutions, and response rates. Am J Hosp Palliat Care. 2017;34(7):654-664.
Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606-613.
Inagaki M, Ohtsuki T, Yonemoto N, et al. Validity of the Patient Health Questionnaire (PHQ)-9 and PHQ-2 in general internal medicine primary care at a Japanese rural hospital: a cross-sectional study. Gen Hosp Psychiatr. 2013;35(6):592-597.
Shear KM, Jackson CT, Essock SM, Donahue SA, Felton CJ. Screening for complicated grief among Project Liberty service recipients 18 months after September 11, 2001. Psychiatr Serv. 2006;57(9):1291-1297.
Ito M, Nakajima S, Fujisawa D, et al. Brief measure for screening complicated grief: reliability and discriminant validity. PLoS One. 2012;7(2):e31209.
Wasson JH, Sox HC, Neff RK, Goldman L. Clinical prediction rules. Applications and methodological standards. N Engl J Med. 1985;313(13):793-799.
Toll DB, Janssen KJ, Vergouwe Y, Moons KG. Validation, updating and impact of clinical prediction rules: a review. J Clin Epidemiol. 2008;61(11):1085-1094.
Meurer WJ, Tolles J. Logistic regression diagnostics: understanding how well a model predicts outcomes. J Am Med Assoc. 2017;317(10):1068-1069.
Moons KG, Harrell FE, Steyerberg EW. Should scoring rules be based on odds ratios or regression coefficients?. J Clin Epidemiol. 2002;55(10):1054-1055.
Laupacis A, Sekar N, Stiell IG. Clinical prediction rules. A review and suggested modifications of methodological standards. J Am Med Assoc. 1997;277(6):488-494.
Moons KGM, Wolff RF, Riley RD, et al. PROBAST: a tool to assess risk of bias and applicability of prediction model studies: explanation and elaboration. Ann Intern Med. 2019;170(1):W1-W33.
Shear K, Shair H. Attachment, loss, and complicated grief. Dev Psychobiol. 2005;47(3):253-267.
Lobb EA, Kristjanson LJ, Aoun SM, Monterosso L, Halkett GK, Davies A. Predictors of complicated grief: a systematic review of empirical studies. Death Stud. 2010;34(8):673-698.
Shear MK. Clinical practice. Complicated grief. N Engl J Med. 2015;372(2):153-160.
Addington-Hall J. Research sensitivities to palliative care patients. Eur J Cancer Care. 2002;11(3):220-224.
Teno JM. Measuring end-of-life care outcomes retrospectively. J Palliat Med. 2005;8(Suppl 1):S42-S49.
Li J, Prigerson HG. Assessment and associated features of prolonged grief disorder among Chinese bereaved individuals. Compr Psychiatry. 2016;66:9-16.