Helicobacter Infection and Gastric Adenoma.
Helicobacter
autoimmune
familial adenomatosis coli
foveolar-type adenoma
gastric adenoma
gastritis
intestinal tubular adenoma
oxyntic gland adenoma
pyloric gland adenoma
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
05 Jan 2021
05 Jan 2021
Historique:
received:
09
12
2020
accepted:
30
12
2020
entrez:
20
1
2021
pubmed:
21
1
2021
medline:
21
1
2021
Statut:
epublish
Résumé
We aimed to provide insight into the actual frequencies of gastric adenoma types and their association with gastritis status and associated mucosal changes with a focus on Helicobacter infection and the operative link on gastritis assessment (OLGA)/operative link on gastric intestinal metaplasia assessment (OLGIM) staging. From the archive of the Institute of Pathology in Bayreuth, we collected a consecutive series of 1058 gastric adenomas diagnosed between 1987 and 2017. Clinicopathological parameters retrieved from diagnostic reports included adenoma type and localization, associated mucosal changes in antrum and corpus (i.e., type of gastritis, the extent of intestinal metaplasia and atrophy), gender, date of birth, and date of diagnosis. Intestinal-type adenoma was the most frequent adenoma (89.1%), followed by foveolar-type adenoma (4.3%), pyloric gland adenoma (3.4%), adenomas associated with hereditary tumor syndromes (2.8%), and oxyntic gland adenoma (0.4%). Adenomas were found in the background of We found a higher frequency of foveolar-type adenoma than anticipated from the literature. It needs to be questioned whether OLGA/OLGIM staging can be applied to all patients.
Sections du résumé
BACKGROUND
BACKGROUND
We aimed to provide insight into the actual frequencies of gastric adenoma types and their association with gastritis status and associated mucosal changes with a focus on Helicobacter infection and the operative link on gastritis assessment (OLGA)/operative link on gastric intestinal metaplasia assessment (OLGIM) staging.
METHODS
METHODS
From the archive of the Institute of Pathology in Bayreuth, we collected a consecutive series of 1058 gastric adenomas diagnosed between 1987 and 2017. Clinicopathological parameters retrieved from diagnostic reports included adenoma type and localization, associated mucosal changes in antrum and corpus (i.e., type of gastritis, the extent of intestinal metaplasia and atrophy), gender, date of birth, and date of diagnosis.
RESULTS
RESULTS
Intestinal-type adenoma was the most frequent adenoma (89.1%), followed by foveolar-type adenoma (4.3%), pyloric gland adenoma (3.4%), adenomas associated with hereditary tumor syndromes (2.8%), and oxyntic gland adenoma (0.4%). Adenomas were found in the background of
CONCLUSIONS
CONCLUSIONS
We found a higher frequency of foveolar-type adenoma than anticipated from the literature. It needs to be questioned whether OLGA/OLGIM staging can be applied to all patients.
Identifiants
pubmed: 33466325
pii: microorganisms9010108
doi: 10.3390/microorganisms9010108
pmc: PMC7824786
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Gastric Cancer. 2011 Jun;14(2):101-12
pubmed: 21573743
Histopathology. 2017 Mar;70(4):549-557
pubmed: 27767239
Gastrointest Endosc. 2010 Jun;71(7):1150-8
pubmed: 20381801
Virchows Arch. 2003 Feb;442(2):99-106
pubmed: 12596058
Dis Colon Rectum. 1992 Oct;35(10):996-8
pubmed: 1327683
Virchows Arch. 1996 Jul;428(4-5):223-7
pubmed: 8764930
Clin Gastroenterol Hepatol. 2013 Nov;11(11):1374-84
pubmed: 23583466
J Pathol. 2013 Mar;229(4):579-87
pubmed: 23208952
Cancer. 1971 Jun;27(6):1346-55
pubmed: 5088211
Am J Surg Pathol. 2014 Dec;38(12):1618-26
pubmed: 25390638
Gut. 2016 May;65(5):721-5
pubmed: 26927528
Gut. 2002 Oct;51(4):485-9
pubmed: 12235068
Am J Surg Pathol. 2008 Apr;32(4):524-33
pubmed: 18300795
Am J Surg Pathol. 1999 Feb;23(2):153-8
pubmed: 9989841
Hum Pathol. 2005 Mar;36(3):228-33
pubmed: 15791566
Am J Gastroenterol. 2009 Jun;104(6):1524-32
pubmed: 19491866
Am J Surg Pathol. 2012 Jul;36(7):1030-5
pubmed: 22472957
Am J Gastroenterol. 2016 Aug;111(8):1104-13
pubmed: 27185078
Virchows Arch. 2003 Apr;442(4):317-21
pubmed: 12715167
Int J Surg Pathol. 2016 May;24(3):185-99
pubmed: 26721304
Am J Surg Pathol. 2014 Jun;38(6):784-92
pubmed: 24518125
Virchows Arch. 1999 Oct;435(4):452-7
pubmed: 10526011
Endoscopy. 2010 Aug;42(8):620-6
pubmed: 20623445
Mod Pathol. 2020 Feb;33(2):206-216
pubmed: 31375767
Pathol Int. 1996 Nov;46(11):908-17
pubmed: 8970203
Am J Surg Pathol. 2002 Oct;26(10):1276-85
pubmed: 12360042
Gut. 2003 Aug;52(8):1111-6
pubmed: 12865267
Am J Surg Pathol. 2010 Nov;34(11):1591-8
pubmed: 20975338
Front Gastrointest Res. 1979;4:164-72
pubmed: 428888
Virchows Arch. 2010 Nov;457(5):529-36
pubmed: 20827489
J Clin Pathol. 2014 Oct;67(10):883-90
pubmed: 25092673
Gastric Cancer. 2006;9(3):177-84
pubmed: 16952035
Histopathology. 2015 Nov;67(5):689-98
pubmed: 25832318
Histopathology. 2016 May;68(6):825-33
pubmed: 26335020
Gut. 2000 Aug;47(2):251-5
pubmed: 10896917
Endoscopy. 2014 Feb;46(2):153-7
pubmed: 24338239
Dig Liver Dis. 2008 Aug;40(8):650-8
pubmed: 18424244
Am J Surg Pathol. 2009 Feb;33(2):186-93
pubmed: 18830123
Endoscopy. 2015 Sep;47(9):829-54
pubmed: 26317585
J Clin Pathol. 1985 Jun;38(6):622-30
pubmed: 4008664
APMIS. 1988 Jul;96(7):627-34
pubmed: 3408590
Mod Pathol. 2003 Aug;16(8):786-95
pubmed: 12920223
Am J Surg Pathol. 2000 Feb;24(2):167-76
pubmed: 10680883
Am J Surg Pathol. 2014 Mar;38(3):389-93
pubmed: 24525509