Defining the Scope of Antimicrobial Stewardship Interventions on the Prescription Quality of Antibiotics for Surgical Intra-Abdominal Infections.
antibiotic prescription behavior
antimicrobial stewardship
post-operative antibiotic treatment
surgical intra-abdominal infections
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
14 Jan 2021
14 Jan 2021
Historique:
received:
29
12
2020
revised:
08
01
2021
accepted:
11
01
2021
entrez:
20
1
2021
pubmed:
21
1
2021
medline:
21
1
2021
Statut:
epublish
Résumé
The aim of this study was to assess the impact of antimicrobial stewardship interventions on surgical antibiotic prescription behavior in the management of non-elective surgical intra-abdominal infections, focusing on postoperative antibiotic use, including the appropriateness of indications. A single-center quality improvement study with retrospective evaluation of the impact of antimicrobial stewardship measures on optimizing antibacterial use in intra-abdominal infections requiring emergency surgery was performed. The study was conducted in a tertiary hospital in Germany from January 1, 2016, to January 30, 2020, three years after putting a set of antimicrobial stewardship standards into effect. 767 patients were analyzed ( Postoperative antibiotic use for intra-abdominal infections could be significantly reduced by antimicrobial stewardship interventions. The identification of inappropriate indications remains a key target for antimicrobial stewardship programs.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of this study was to assess the impact of antimicrobial stewardship interventions on surgical antibiotic prescription behavior in the management of non-elective surgical intra-abdominal infections, focusing on postoperative antibiotic use, including the appropriateness of indications.
METHODS
METHODS
A single-center quality improvement study with retrospective evaluation of the impact of antimicrobial stewardship measures on optimizing antibacterial use in intra-abdominal infections requiring emergency surgery was performed. The study was conducted in a tertiary hospital in Germany from January 1, 2016, to January 30, 2020, three years after putting a set of antimicrobial stewardship standards into effect.
RESULTS
RESULTS
767 patients were analyzed (
CONCLUSIONS
CONCLUSIONS
Postoperative antibiotic use for intra-abdominal infections could be significantly reduced by antimicrobial stewardship interventions. The identification of inappropriate indications remains a key target for antimicrobial stewardship programs.
Identifiants
pubmed: 33466628
pii: antibiotics10010073
doi: 10.3390/antibiotics10010073
pmc: PMC7828676
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Am Surg. 2013 Dec;79(12):1269-72
pubmed: 24351354
Chirurg. 1987 Feb;58(2):84-92
pubmed: 3568820
N Engl J Med. 2015 May 21;372(21):1996-2005
pubmed: 25992746
World J Emerg Surg. 2017 Jul 10;12:29
pubmed: 28702076
J Antimicrob Chemother. 2018 Apr 1;73(4):1077-1083
pubmed: 29309607
Clin Infect Dis. 2016 May 15;62(10):e51-77
pubmed: 27080992
Surg Infect (Larchmt). 2016 Aug;17(4):485-90
pubmed: 27135794
Clin Infect Dis. 2013 Jul;57(2):188-96
pubmed: 23572483
Clin Microbiol Infect. 2011 Nov;17(11):1746-51
pubmed: 20840333
World J Emerg Surg. 2020 May 7;15(1):32
pubmed: 32381121
Surg Infect (Larchmt). 2017 Jan;18(1):1-76
pubmed: 28085573
Infect Control Hosp Epidemiol. 2012 Apr;33(4):427-9
pubmed: 22418644
Am J Infect Control. 1999 Apr;27(2):97-132; quiz 133-4; discussion 96
pubmed: 10196487
Am J Surg. 2005 Apr;189(4):395-404
pubmed: 15820449
JAMA. 2017 Jul 18;318(3):291-292
pubmed: 28719679
Clin Infect Dis. 2016 Oct 1;63(7):889-93
pubmed: 27486116
World J Emerg Surg. 2017 Aug 1;12:34
pubmed: 28775763
Surg Infect (Larchmt). 2016 Apr;17(2):224-8
pubmed: 26719984
JAMA. 2016 Feb 23;315(8):801-10
pubmed: 26903338
J Hepatobiliary Pancreat Sci. 2013 Jan;20(1):1-7
pubmed: 23307006
Clin Infect Dis. 2010 Jan 15;50(2):133-64
pubmed: 20034345
Am Surg. 2014 Sep;80(9):878-83
pubmed: 25197874
J Antimicrob Chemother. 2015 Apr;70(4):1226-9
pubmed: 25505004
Ann Surg. 2004 Aug;240(2):205-13
pubmed: 15273542
Antibiotics (Basel). 2016 Feb 15;5(1):
pubmed: 27025526
Lancet Infect Dis. 2016 Jul;16(7):847-856
pubmed: 26947617
Lancet Glob Health. 2018 Jun;6(6):e619-e629
pubmed: 29681513
Clin Microbiol Infect. 2009 Apr;15 Suppl 3:12-5
pubmed: 19366364
Cochrane Database Syst Rev. 2017 Feb 09;2:CD003543
pubmed: 28178770
Cochrane Database Syst Rev. 2017 Feb 9;2:ED000119
pubmed: 28211043